Use of fibrinogen and fibrin D-dimer in prediction of arterial thrombotic events

GDO Lowe, A Rumley - Thrombosis and haemostasis, 1999 - thieme-connect.com
There is increasing clinical and laboratory interest in the measurement of both plasma
fibrinogen and fibrin D-dimer to predict arterial thrombotic events, such as cardiovascular …

Determinants of Fibrin d-Dimer in the Edinburgh Artery Study

AJ Lee, FGR Fowkes, GDO Lowe… - … thrombosis, and vascular …, 1995 - Am Heart Assoc
There is growing evidence that fibrin d-dimer is associated with coronary and peripheral
atherosclerosis. Using data from the Edinburgh Artery Study, we examined the distribution of …

Fibrin D-dimer and cardiovascular risk

GDO Lowe - Seminars in vascular medicine, 2005 - thieme-connect.com
Fibrin D-dimer, the most commonly used clinical assay for detection of coagulation activation
and in vivo fibrin formation and lysis in circulating blood, has been associated with risks of …

Fibrinogen and its degradation products as thrombotic risk factors

GDO Lowe, A Rumley - Annals of the New York Academy of …, 2001 - Wiley Online Library
Recent meta‐analyses of prospective studies have shown that plasma levels of both
fibrinogen and fibrin D‐dimer are independent predictors of ischemic heart disease …

The fibrin assay comparison trial (FACT)

CE Dempfle, S Zips, H Ergül, DL Heene… - Thrombosis and …, 2001 - thieme-connect.com
Although D-dimer has gained widespread clinical use as a parameter for detection of in vivo
fibrin formation, the issue of standardization of D-dimer assays remains to be resolved. The …

Fibrin D-dimer, markers of coagulation activation and the risk of major ischaemic heart disease in the caerphilly study

GDO Lowe, A Rumley, PM Sweetnam… - Thrombosis and …, 2001 - thieme-connect.com
We have previously reported that plasma fibrin D-dimer (a marker of turnover of cross-linked
fibrin) showed a strong and independent association with incident ischaemic heart disease …

[HTML][HTML] Elevated levels of soluble fibrin or D‐dimer indicate high risk of thrombosis

H Wada, T Kobayashi, Y Abe, T Hatada… - Journal of Thrombosis …, 2006 - Elsevier
Background: Fibrin‐related markers such as soluble fibrin (SF) and D‐dimer are considered
useful for the diagnosis of thrombosis. However, the evidence for diagnosis of thrombosis by …

Harmonisation of D-dimer—A call for action

C Longstaff, D Adcock, JD Olson… - Thrombosis …, 2016 - thrombosisresearch.com
D-dimer is a stable, terminal product of fibrin degradation in plasma. In the 1970s, Gaffney
and colleagues introduced the concept of D-dimer measurement as a biomarker of …

Fibrinogen, D-dimer and thrombin-antithrombin complexes in a random population sample: relationships with other cardiovascular risk factors

C Giansante, N Fiotti, L Cattin… - Thrombosis and …, 1994 - thieme-connect.com
Fibrinogen is an independent risk factor for cardiovascular disease and both D-Dimer and
Thrombin-Antithrombin complexes may be suitable as laboratory markers of deep venous …

Plasma fibrin D-dimer levels and risk of stable coronary artery disease: results of a large case-control study

W Koenig, D Rothenbacher, A Hoffmeister… - … , and vascular biology, 2001 - Am Heart Assoc
Increased levels of fibrin D-dimer are indicative of a hypercoagulable state, as found in
acute coronary syndromes. Few well-controlled studies have assessed D-dimers in patients …