Clinical features of septic discitis in the UK: a retrospective case ascertainment study and review of management recommendations

N Hopkinson, K Patel - Rheumatology international, 2016 - Springer
Septic discitis is a rare but important cause of spinal pain caused by intervertebral disc
infection. This retrospective observational case series analysis will examine the clinical …

Improved diagnosis specificity in bone and joint infections using molecular techniques

V Fihman, D Hannouche, V Bousson, T Bardin, F Liote… - Journal of Infection, 2007 - Elsevier
OBJECTIVES: The microbiological diagnosis of osteoarticular infections currently relies on
microbiological cultures, to specifically target treatment. However, these conventional …

The role of histology in the diagnosis of spondylodiscitis: correlation with clinical and microbiological findings

E Iwata, M Scarborough, G Bowden… - The Bone & Joint …, 2019 - boneandjoint.org.uk
Aims The aim of this study was to determine the diagnostic utility of histological analysis in
spinal biopsies for spondylodiscitis (SD). Patients and Methods Clinical features, radiology …

CT-guided biopsy in suspected spondylodiscitis: microbiological yield, impact on antimicrobial treatment, and relationship with outcome

Ö Kasalak, M Wouthuyzen-Bakker, HJA Adams… - Skeletal Radiology, 2018 - Springer
Purpose To investigate the clinical impact of CT-guided biopsy, as performed in routine
clinical practice, in patients with suspected spondylodiscitis on MRI in terms of culture yield …

Nested polymerase chain reaction strategy simultaneously targeting DNA sequences of multiple bacterial species in inflammatory joint diseases. II. Examination of …

J Braun, M Tuszewski, S Ehlers, J Häberle… - The Journal of …, 1997 - europepmc.org
Objective Bacteria play a crucial pathogenetic role in reactive arthritis (ReA) and other forms
of spondyloarthropathy (SpA) and in Lyme arthritis. Although there is evidence of local …

Diagnostic yield of repeat CT-guided biopsy for suspected infectious spondylodiscitis

GJ Czuczman, DE Marrero, AJ Huang, JC Mandell… - Skeletal Radiology, 2018 - Springer
Objective The purpose of this study was to examine the yield of repeat CT-guided biopsy in
patients with suspected infectious spondylodiscitis following an initial biopsy with negative …

Infectious spondylodiscitis

L Cottle, T Riordan - Journal of Infection, 2008 - Elsevier
OBJECTIVES: To review the available literature on infectious spondylodiscitis and provide
recommendations on management, particularly identification of the causative agent and …

Development of a novel, rapid processing protocol for polymerase chain reaction-based detection of bacterial infections in synovial fluids

BD Mariani, MJ Levine, RE Booth, RS Tuan - Molecular biotechnology, 1995 - Springer
We describe the development of a molecular detection system designed for use with
synovial fluid (SF)-based infections. The methodology employs a lysis/extraction procedure …

Benefits of polymerase chain reaction combined with culture for the diagnosis of bone and joint infections: a prospective test performance study

H Jacquier, V Fihman, R Amarsy… - Open Forum …, 2019 - academic.oup.com
Background The microbiological diagnosis of bone and joint infections (BJI) currently relies
on cultures, and the relevance of molecular methods is still debated. The aim of this study …

The detection of DNA from a range of bacterial species in the joints of patients with a variety of arthritides using a nested, broad-range polymerase chain reaction.

NZ Wilkinson, GH Kingsley, HW Jones… - Rheumatology …, 1999 - academic.oup.com
OBJECTIVE: Bacteria have been implicated in the pathogenesis of many types of
inflammatory arthritides. The aim of this study was to identify any bacterial DNA in synovial …