Prussian blue nanozyme with multienzyme activity reduces colitis in mice

J Zhao, X Cai, W Gao, L Zhang, D Zou… - … applied materials & …, 2018 - ACS Publications
The overproduction of reactive oxygen species (ROS) is central to the progression of
inflammatory bowel disease (IBD), which may be the potential therapeutic target. Prussian …

[HTML][HTML] Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease

J Zhao, W Gao, X Cai, J Xu, D Zou, Z Li, B Hu… - Theranostics, 2019 - ncbi.nlm.nih.gov
The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel
disease (IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS …

Zero‐valence selenium‐enriched Prussian blue nanozymes reconstruct intestinal barrier against inflammatory bowel disease via inhibiting Ferroptosis and T cells …

D Zhu, H Wu, K Jiang, Y Xu, Z Miao… - Advanced Healthcare …, 2023 - Wiley Online Library
The structural disruption of mechanical barrier and dysfunction of immune barrier in
intestinal, are important factors, that aggravate inflammatory bowel disease (IBD). To tackle …

Prussian blue nanozymes prevent anthracycline-induced liver injury by attenuating oxidative stress and regulating inflammation

H Bai, F Kong, K Feng, X Zhang, H Dong… - … applied materials & …, 2021 - ACS Publications
Anthracycline-induced liver injury (AILI) is becoming an increasingly serious and potential
clinical complication and is linked to reactive oxygen species (ROS) production and …

Antioxidant and anti-inflammatory activities of Prussian blue nanozyme promotes full-thickness skin wound healing

A Sahu, J Jeon, MS Lee, HS Yang, G Tae - Materials Science and …, 2021 - Elsevier
Excessive reactive oxygen species (ROS) and unresolved inflammations are the major
causes of impaired wound healing as they overwhelm the cellular antioxidant system and …

The progression of inorganic nanoparticles and natural products for inflammatory bowel disease

Q Li, L Lin, C Zhang, H Zhang, Y Ma, H Qian… - Journal of …, 2024 - Springer
There is a growing body of evidence indicating a close association between inflammatory
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …

Oral metal‐free melanin nanozymes for natural and durable targeted treatment of inflammatory bowel disease (IBD)

Q Huang, Y Yang, Y Zhu, Q Chen, T Zhao, Z Xiao… - Small, 2023 - Wiley Online Library
Oral antioxidant nanozymes bring great promise for inflammatory bowel disease (IBD)
treatment. To efficiently eliminate reactive oxygen species (ROS), various metal‐based …

A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease

F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …

Prussian blue nanozymes: progress, challenges, and opportunities

H He, M Long, Y Duan, N Gu - Nanoscale, 2023 - pubs.rsc.org
Prussian Blue Nanozymes (PBNZs) have emerged as highly efficient agents for reactive
oxygen species (ROS) elimination, owing to their multiple enzyme-like properties …

Prussian blue nanoparticles as multienzyme mimetics and reactive oxygen species scavengers

W Zhang, S Hu, JJ Yin, W He, W Lu, M Ma… - Journal of the …, 2016 - ACS Publications
The generation of reactive oxygen species (ROS) is an important mechanism of
nanomaterial toxicity. We found that Prussian blue nanoparticles (PBNPs) can effectively …