Malignant pleural effusion cells show aberrant glucose metabolism gene expression
Malignant pleural effusion (MPE) accompanying lung adenocarcinoma indicates poor
prognosis and early metastasis. This study aimed to identify genes related to MPE formation …
prognosis and early metastasis. This study aimed to identify genes related to MPE formation …
Molecular profiling of malignant pleural effusion in metastatic non–small-cell lung carcinoma. The effect of preanalytical factors
J Carter, JA Miller, D Feller-Kopman… - Annals of the …, 2017 - atsjournals.org
Rationale: Non–small-cell lung cancer (NSCLC)–associated malignant pleural effusions
(MPEs) are sometimes the only available specimens for molecular analysis. Objectives: This …
(MPEs) are sometimes the only available specimens for molecular analysis. Objectives: This …
Single‐cell transcriptomics reveal metastatic CLDN4+ cancer cells underlying the recurrence of malignant pleural effusion in patients with advanced non‐small‐cell …
X Zhang, X Wang, Y Wen, S Chen… - Clinical and …, 2024 - Wiley Online Library
Background Recurrent malignant pleural effusion (MPE) resulting from non‐small‐cell lung
cancer (NSCLC) is easily refractory to conventional therapeutics and lacks predictive …
cancer (NSCLC) is easily refractory to conventional therapeutics and lacks predictive …
ALDH1 and SALL4 expression in cell block samples from patients with lung adenocarcinoma and malignant pleural effusion
T Kanayama, T Taniguchi, H Tomita, A Niwa… - Diagnostics, 2021 - mdpi.com
Malignant pleural effusion (MPE) can accompany advanced lung adenocarcinoma. Recent
studies suggest that MPE could contain a heterogeneous subpopulation of cells with stem …
studies suggest that MPE could contain a heterogeneous subpopulation of cells with stem …
Pulmonary adenocarcinoma in malignant pleural effusion enriches cancer stem cell properties during metastatic cascade
Background Metastasis occurs in a series of discrete steps involving invasion, angiogenesis,
lymphovascular space permeation, and establishment of secondary tumors. Malignant …
lymphovascular space permeation, and establishment of secondary tumors. Malignant …
mRNA markers associated with malignant pleural effusion
Malignant pleural effusions (MPE) commonly result from malignant tumors and represent
advanced-stage cancers. Thus, in clinical practice, early recognition of MPE is valuable …
advanced-stage cancers. Thus, in clinical practice, early recognition of MPE is valuable …
A multicancer malignant pleural effusion diagnostic test using hexokinase 2 and single-cell sequencing
J Chen, Y Yang, Z Wang, X Shen, Z Zhang… - Clinical …, 2022 - academic.oup.com
Background Malignant pleural effusion (MPE) represents advanced malignant disease with
poor prognosis. To date, pleural effusion cytology remains the best test to diagnose MPE but …
poor prognosis. To date, pleural effusion cytology remains the best test to diagnose MPE but …
[HTML][HTML] Multiplexed molecular profiling of lung cancer using pleural effusion
H Akamatsu, Y Koh, H Kenmotsu, T Naito… - Journal of Thoracic …, 2014 - Elsevier
Introduction: Pleural effusion is frequently observed in patients with advanced lung cancer.
Although effusion can be obtained less invasively and repeatedly, its use in multiplexed …
Although effusion can be obtained less invasively and repeatedly, its use in multiplexed …
Molecular profiling of malignant pleural effusions with next generation sequencing (NGS): evidence that supports its role in cancer management
GΙ Grigoriadou, SM Esagian, HS Ryu… - Journal of Personalized …, 2020 - mdpi.com
Malignant pleural effusions (MPEs) often develop in advanced cancer patients and confer
significant morbidity and mortality. In this review, we evaluated whether molecular profiling …
significant morbidity and mortality. In this review, we evaluated whether molecular profiling …
Pleural effusion in lung cancer: more questions than answers
ME Froudarakis - Respiration, 2012 - karger.com
Lung cancer remains the most common fatal malignancy, despite more aggressive
therapies. Few patients will survive 5 years, as up to 80% of the patients will present with …
therapies. Few patients will survive 5 years, as up to 80% of the patients will present with …