Mucoadhesive probiotic backpacks with ROS nanoscavengers enhance the bacteriotherapy for inflammatory bowel diseases
Inflammatory bowel diseases (IBDs) are often associated with elevated levels of reactive
oxygen species (ROS) and highly dysregulated gut microbiota. In this study, we synthesized …
oxygen species (ROS) and highly dysregulated gut microbiota. In this study, we synthesized …
Modified prebiotic-based “shield” armed probiotics with enhanced resistance of gastrointestinal stresses and prolonged intestinal retention for synergistic alleviation of …
Oral administration of probiotics is a promising method to alleviate inflammatory bowel
diseases (IBDs). However, gastrointestinal environmental sensitivity and inferior intestinal …
diseases (IBDs). However, gastrointestinal environmental sensitivity and inferior intestinal …
Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery
J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
Responsively Degradable Nanoarmor‐Assisted Super Resistance and Stable Colonization of Probiotics for Enhanced Inflammation‐Targeted Delivery
L Zhu, T Yu, W Wang, T Xu, W Geng, N Li… - Advanced …, 2024 - Wiley Online Library
Manipulation of the gut microbiota using oral microecological preparations has shown great
promise in treating various inflammatory disorders. However, delivering these preparations …
promise in treating various inflammatory disorders. However, delivering these preparations …
Prodrug integrated envelope on probiotics to enhance target therapy for ulcerative colitis
K Zhang, L Zhu, Y Zhong, L Xu, C Lang… - Advanced …, 2023 - Wiley Online Library
Ulcerative colitis (UC), affecting millions of patients worldwide, is associated with disorders
of the gut microbiota. Probiotics‐based therapy positively regulating the community structure …
of the gut microbiota. Probiotics‐based therapy positively regulating the community structure …
[HTML][HTML] Reactive oxygen species-responsive nanocarrier ameliorates murine colitis by intervening colonic innate and adaptive immune responses
Ulcerative colitis (UC) is a chronic or relapsing inflammatory disease with limited therapeutic
outcomes. Pterostilbene (PSB) is a polyphenol-based anti-oxidant that has received …
outcomes. Pterostilbene (PSB) is a polyphenol-based anti-oxidant that has received …
Colon-Targeting Angelica sinensis Polysaccharide Nanoparticles with Dual Responsiveness for Alleviation of Ulcerative Colitis
Y Xu, BW Zhu, R Sun, X Li, D Wu… - ACS Applied Materials & …, 2023 - ACS Publications
Intestinal immune dysfunction and gut microbiota dysbiosis are critically causative factors in
the pathogenesis of ulcerative colitis (UC); however, the current first-line drugs for UC …
the pathogenesis of ulcerative colitis (UC); however, the current first-line drugs for UC …
Gastrointestinal Microenvironment Responsive Nanoencapsulation of Probiotics and Drugs for Synergistic Therapy of Intestinal Diseases
P Peng, T Feng, X Yang, C Nie, L Yu, R Ding, Q Zhou… - ACS …, 2023 - ACS Publications
The gut microbiota are prominent in preserving intestinal environmental homeostasis and
managing human health, and their dysbiosis has been directly related to many kinds of …
managing human health, and their dysbiosis has been directly related to many kinds of …
Stimulation-responsive mucoadhesive probiotics for inflammatory bowel disease treatment by scavenging reactive oxygen species and regulating gut microbiota
QX Huang, JL Liang, CH Yang, K Li, MT Niu, JX Fan… - Biomaterials, 2023 - Elsevier
Inflammatory bowel disease (IBD) is characterized by the high level of reactive oxygen
species (ROS) and highly dysfunctional intestinal flora. Here, a stimulation-responsive …
species (ROS) and highly dysfunctional intestinal flora. Here, a stimulation-responsive …
Reactive Oxygen Species‐Activated CO Versatile Nanomedicine with Innate Gut Immune and Microbiome Remodeling Effects for Treating Inflammatory Bowel …
Y Zeng, M Fan, Q Zhou, D Chen, T Jin… - Advanced Functional …, 2023 - Wiley Online Library
Abnormal activation of the gut mucosal immune system and a highly dysregulated gut
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …