Nanozyme-based strategies for efficient theranostics of brain diseases

R Xu, S Zhang, P Wang, R Zhang, P Lin, Y Wang… - Coordination Chemistry …, 2024 - Elsevier
Oxidative stress emerges as a critical mechanism underlying the development and
progression of various brain diseases, arising from either increased generation of reactive …

Nanozyme enabled protective therapy for neurological diseases

F Cheng, S Kotha, M Fu, Q Yang, H Wang, W He… - Nano Today, 2024 - Elsevier
Nanozymes are nanomaterials that mimic enzymatic activities found in natural human
biological processes. Nanozymes can perform reactive oxidative species (ROS) scavenging …

Bioactive material-based nanozymes with multifunctional attributes for biomedicine: expanding antioxidant therapeutics for neuroprotection, cancer, and anti …

DO Lopez-Cantu, RB González-González… - Coordination Chemistry …, 2022 - Elsevier
Considering the biochemical rationale, the deployments of enzymes as therapeutic targets
against several oxidative stress-related diseases have been hindered by the limitations of …

Catalytic nanozymes for central nervous system disease

K Chen, S Sun, J Wang, XD Zhang - Coordination Chemistry Reviews, 2021 - Elsevier
The central nervous system (CNS) is a centralized control system for the human body, and
minor lesions or injuries will cause inestimable consequences. Due to high oxygen …

[HTML][HTML] The applications of nanozymes in neurological diseases: from mechanism to design

Y Zhang, L Zhang, M Wang, P Li - Theranostics, 2023 - ncbi.nlm.nih.gov
Nanozymes are a class of nanomaterials with enzyme-like catalytic activities. Due to their
multiple catalytic activities, as well as their good stability, modifiable activity and other …

Nanozyme‐enabled treatment of cardio‐and cerebrovascular diseases

Y Zhang, W Liu, X Wang, Y Liu, H Wei - Small, 2023 - Wiley Online Library
Cardio‐and cerebrovascular diseases are two major vascular‐related diseases that lead to
death worldwide. Reactive oxygen species (ROS) play a vital role in the occurrence and …

Multi-enzyme activity nanozymes for biosensing and disease treatment

L Su, S Qin, Z Xie, L Wang, K Khan, AK Tareen… - Coordination Chemistry …, 2022 - Elsevier
In cells, multi-step biochemical reactions catalyzed by multi-enzyme biocatalysts are critical.
While, multi-enzyme biocatalysts have evolved to catalyze these diverse reactions in …

Nanozyme antioxidants as emerging alternatives for natural antioxidants: Achievements and challenges in perspective

M Ghorbani, H Derakhshankhah, S Jafari, S Salatin… - Nano Today, 2019 - Elsevier
Nanozymes are nanoparticulated structures with the inherent enzymatic activities, which
their advances in bio/nanomedicine field are progressively growing regarding their …

Recent advancements in the formulation of nanomaterials-based nanozymes, their catalytic activity, and biomedical applications

S Singh, N Rai, H Tiwari, P Gupta, A Verma… - ACS Applied Bio …, 2023 - ACS Publications
Nanozymes are nanoparticles with intrinsic enzyme-mimicking properties that have become
more prevalent because of their ability to outperform conventional enzymes by overcoming …

Chemical design of nanozymes for biomedical applications

M Wei, J Lee, F Xia, P Lin, X Hu, F Li, D Ling - Acta biomaterialia, 2021 - Elsevier
With the advancement of nanochemistry, artificial nanozymes with high catalytic stability, low
manufacturing and storage cost, and greater design flexibility over natural enzymes, have …