Chronic alcohol feeding inhibits physiological and molecular parameters of intestinal and renal riboflavin transport

VS Subramanian, SB Subramanya… - … of Physiology-Cell …, 2013 - journals.physiology.org
Vitamin B2 (riboflavin, RF) is essential for normal human health. Mammals obtain RF from
exogenous sources via intestinal absorption and prevent its urinary loss by reabsorption in …

Molecular mechanisms mediating the adaptive regulation of intestinal riboflavin uptake process

VS Subramanian, A Ghosal, R Kapadia… - PLoS …, 2015 - journals.plos.org
The intestinal absorption process of vitamin B2 (riboflavin, RF) is carrier-mediated, and all
three known human RF transporters, ie, hRFVT-1,-2, and-3 (products of the SLC52A1, 2 & 3 …

Sodium butyrate enhances intestinal riboflavin uptake via induction of expression of riboflavin transporter-3 (RFVT3)

VS Subramanian, S Sabui, CW Heskett… - Digestive diseases and …, 2019 - Springer
Background Uptake of riboflavin (RF) by intestinal epithelial cells occurs via a specific carrier-
mediated process that involves the apically localized RF transporter-3 (RFVT3). Previous …

Effect of the proinflammatory cytokine TNF-α on intestinal riboflavin uptake: inhibition mediated via transcriptional mechanism (s)

KY Anandam, OA Alwan… - … of Physiology-Cell …, 2018 - journals.physiology.org
Riboflavin (RF), is essential for normal cellular metabolism/function. Intestinal RF absorption
occurs via a specific carrier-mediated process that involves the apical transporter RFVT-3 …

Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption

VS Subramanian, N Lambrecht… - American Journal of …, 2016 - journals.physiology.org
Riboflavin (RF) is indispensable for normal cell metabolism, proliferation, and growth. The
RFVT-3 protein (product of the Slc52a3 gene) is expressed in the gut with the expression …

Functional involvement of RFVT3/SLC52A3 in intestinal riboflavin absorption

H Yoshimatsu, A Yonezawa, Y Yao… - American Journal …, 2014 - journals.physiology.org
Riboflavin, also known as vitamin B2, is transported across the biological membrane into
various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small …

Identification and characterization of the minimal 5′-regulatory region of the human riboflavin transporter-3 (SLC52A3) in intestinal epithelial cells

A Ghosal, S Sabui, HM Said - American Journal of …, 2015 - journals.physiology.org
The human riboflavin (RF) transporter-3 (product of the SLC52A3 gene) plays an important
role in intestinal RF absorption. Our aims in this study were to identify the minimal 5 …

Mechanism of riboflavine uptake by Caco-2 human intestinal epithelial cells

HM Said, TY Ma - American Journal of Physiology …, 1994 - journals.physiology.org
The cellular and molecular regulation of intestinal absorption of the water-soluble vitamin
riboflavine (RF) is poorly understood. The availability of a suitable in vitro cultured system …

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells

VS Subramanian, L Rapp… - American Journal of …, 2011 - journals.physiology.org
The water-soluble vitamin B2 (riboflavin, RF) is an essential micronutrient for normal cell
function and survival. Recent studies have identified a role for the human riboflavin …

Identification of transmembrane protein 237 as a novel interactor with the intestinal riboflavin transporter-3 (RFVT-3): role in functionality and cell biology

S Sabui, VS Subramanian, Q Pham… - American Journal of …, 2019 - journals.physiology.org
The apically localized riboflavin (RF) transporter-3 (RFVT-3) is involved in intestinal
absorption of vitamin B2. Previous studies have characterized different physiological …