Multi-shell nanocomposites based multienzyme mimetics for efficient intracellular antioxidation

Y Ai, J You, J Gao, J Wang, H Sun, M Ding, Q Liang - Nano Research, 2021 - Springer
Oxidative stress is associated with many acute and chronic inflammatory diseases.
Development of nanomaterial-based enzyme mimetics for reactive oxygen species (ROS) …

Nanocomposite-based dual enzyme system for broad-spectrum scavenging of reactive oxygen species

M Pavlovic, S Muráth, X Katona, NB Alsharif… - Scientific Reports, 2021 - nature.com
A broad-spectrum reactive oxygen species (ROS)-scavenging hybrid material (CASCADE)
was developed by sequential adsorption of heparin (HEP) and poly (L-lysine)(PLL) …

Multienzymatic antioxidant activity of manganese-based nanoparticles for protection against oxidative cell damage

Y Zhang, L Chen, R Sun, R Lv, T Du, Y Li… - ACS Biomaterials …, 2022 - ACS Publications
Oxidative stress is related to many diseases, but available clinical treatment methods are
currently limited. Exploitation of enzyme-mimicking nanomaterials (nanozymes) is a …

Selenium‐based nanozyme as biomimetic antioxidant machinery

Y Huang, Z Liu, C Liu, Y Zhang… - Chemistry–A European …, 2018 - Wiley Online Library
A self‐assembly nanocomposite was designed to mimic intracellular enzymatic and non‐
enzymatic antioxidants‐constituted antioxidant defense machinery. In this work, selenium …

Salen-manganese complex-based nanozyme with enhanced superoxide-and catalase-like activity for wound disinfection and anti-inflammation

X Dai, Q Xu, Y Li, L Yang, Y Zhang, X Liu… - Chemical Engineering …, 2023 - Elsevier
Skin wound healing remains a key challenge owing to its vulnerability to pathogen infection,
oxidative stress and persistent inflammatory response. Herein, a salen-manganese complex …

ROS scavenging Mn 3 O 4 nanozymes for in vivo anti-inflammation

J Yao, Y Cheng, M Zhou, S Zhao, S Lin, X Wang… - Chemical …, 2018 - pubs.rsc.org
Reactive oxygen species (ROS)-induced oxidative stress is linked to various diseases,
including cardiovascular disease and cancer. Though highly efficient natural ROS …

Antioxidant nanozymes as next-generation therapeutics to free radical-mediated inflammatory diseases: A comprehensive review

S Singh - International Journal of Biological Macromolecules, 2024 - Elsevier
Recent developments in exploring the biological enzyme mimicking properties in
nanozymes have opened a separate avenue, which provides a suitable alternative to the …

Enzyme-mimetic antioxidant nanomaterials for ROS scavenging: Design, classification, and biological applications

S Zhou, H Cai, X He, Z Tang, S Lu - Coordination Chemistry Reviews, 2024 - Elsevier
Reactive oxygen species (ROS) perform vital functions in numerous life processes and
significantly affect physiological activities in different organ systems in the human body …

Self‐assembly of multi‐nanozymes to mimic an intracellular antioxidant defense system

Y Huang, Z Liu, C Liu, E Ju, Y Zhang… - Angewandte …, 2016 - Wiley Online Library
In this work, for the first time, we constructed a novel multi‐nanozymes cooperative platform
to mimic intracellular antioxidant enzyme‐based defense system. V2O5 nanowire served as …

A manganese oxide nanozyme prevents the oxidative damage of biomolecules without affecting the endogenous antioxidant system

N Singh, MA Savanur, S Srivastava, P D'Silva… - Nanoscale, 2019 - pubs.rsc.org
Biocompatible nanoparticles with an intrinsic ability to mimic the cellular antioxidant
enzymes are potential candidates for the development of new therapeutics for various …