Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

S Matsushita, M Robert-Guroff, J Rusche… - Journal of …, 1988 - Am Soc Microbiol
A monoclonal antibody was produced to the exterior envelope glycoprotein (gp120) of the
human T-cell lymphotropic virus (HTLV)-IIIB isolate of the human immunodeficiency virus …

Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins.

PA Broliden, A von Gegerfelt… - Proceedings of the …, 1992 - National Acad Sciences
Four major neutralizing regions of the human immunodeficiency virus type 1 (HIV-1)
envelope glycoprotein were identified and characterized with a panel of 80 HIV-1 antibody …

Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles

MK Gorny, L Stamatatos, B Volsky, K Revesz… - Journal of …, 2005 - Am Soc Microbiol
The selection of human monoclonal antibodies (MAbs) specific for human immunodeficiency
virus (HIV) type 1 by binding assays may fail to identify Abs to quaternary epitopes on the …

Induction of anti‐HIV neutralizing antibodies by synthetic peptides.

TC Chanh, GR Dreesman, P Kanda, GP Linette… - The EMBO …, 1986 - embopress.org
Two synthetic peptides containing amino acid sequences analogous to the envelope
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

J Goudsmit, C Debouck, RH Meloen… - Proceedings of the …, 1988 - National Acad Sciences
Chimpanzees are susceptible to infection by divergent strains of human immunodeficiency
virus type 1 (HIV-1), none of which cause clinical or immunological abnormalities …

Antibody neutralization-resistant primary isolates of human immunodeficiency virus type 1

PWHI Parren, M Wang, A Trkola, JM Binley… - Journal of …, 1998 - Am Soc Microbiol
Although typical primary isolates of human immunodeficiency virus type 1 (HIV-1) are
relatively neutralization resistant, three human monoclonal antibodies and a small number …

Characteristics of a neutralizing monoclonal antibody to the HIV envelope glycoprotein

MA Skinner, R TING, AJ LANGLOIS… - AIDS research and …, 1988 - liebertpub.com
We have studied the biologic and physical properties of a monoclonal antibody that binds to
gp120, the exterior envelope glycoprotein of the human immunodeficiency virus (HIV) strain …

Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope …

MK Gorny, JY Xu, V Gianakakos… - Proceedings of the …, 1991 - National Acad Sciences
Cell lines secreting IgG1 human monoclonal antibodies (mAb) to the envelope glycoprotein,
gp120, of human immunodeficiency virus (HIV) have been produced by transformation of …

HIV-1 antibody-debris or virion?

PWHI Parren, DR Burton, QJ Sattentau - 1997 - cabidigitallibrary.org
It is suggested that the antibody response to HIV-1 envelope proteins is not directed to virus
but instead directed to viral debris (nonnative forms of the HIV-1 envelope released by lysis …

Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual.

AT Profy, PA Salinas, LI Eckler, NM Dunlop… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
Sera from individuals infected by HIV-1 usually neutralize multiple viral isolates. To
determine the extent to which these neutralizing antibodies recognize a principal …