Multifunctional two-dimensional Bi2Se3 nanodiscs for anti-inflammatory therapy of inflammatory bowel diseases

C Zhang, Q Li, J Shan, J Xing, X Liu, Y Ma, H Qian… - Acta Biomaterialia, 2023 - Elsevier
The overexpression of reactive oxygen and nitrogen species (RONS) in the colonic mucosa
destroys the mucosa and its barrier, accelerating the occurrence of inflammatory bowel …

Multifunctional two dimensional Bi 2 Se 3 nanodiscs for combined antibacterial and anti-inflammatory therapy for bacterial infections

J Ouyang, M Wen, W Chen, Y Tan, Z Liu… - Chemical …, 2019 - pubs.rsc.org
A multifunctional platform based on two-dimensional nanomaterials for combined
antibacterial and anti-inflammatory therapy is developed. Bi2Se3 nanodiscs selectively …

Zero‐valence selenium‐enriched Prussian blue nanozymes reconstruct intestinal barrier against inflammatory bowel disease via inhibiting Ferroptosis and T cells …

D Zhu, H Wu, K Jiang, Y Xu, Z Miao… - Advanced Healthcare …, 2023 - Wiley Online Library
The structural disruption of mechanical barrier and dysfunction of immune barrier in
intestinal, are important factors, that aggravate inflammatory bowel disease (IBD). To tackle …

A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease

F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …

Biogenic nanoselenium particles effectively attenuate oxidative stress-induced intestinal epithelial barrier injury by activating the Nrf2 antioxidant pathway

D Song, Y Cheng, X Li, F Wang, Z Lu… - … Applied Materials & …, 2017 - ACS Publications
In the present study, a new form of selenium nanoparticle (biogenic nanoselenium (BNS)
particles) was synthesized using bacteria. The protection of BNS particles against oxidative …

[HTML][HTML] Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease

J Zhao, W Gao, X Cai, J Xu, D Zou, Z Li, B Hu… - Theranostics, 2019 - ncbi.nlm.nih.gov
The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel
disease (IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS …

Rational design of orally administered cascade nanozyme for inflammatory bowel disease therapy

Y Yu, X Zhao, X Xu, C Cai, X Tang, Q Zhang… - Advanced …, 2023 - Wiley Online Library
Inflammatory bowel disease (IBD) affects millions of individuals worldwide annually. Enteric
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …

Tannic acid and zinc ion coordination of nanase for the treatment of inflammatory bowel disease by promoting mucosal repair and removing reactive oxygen and …

C Zhang, Q Li, J Xing, Y Yang, M Zhu, L Lin, Y Yu… - Acta Biomaterialia, 2024 - Elsevier
Colon mucosal overexpression of reactive oxygen and nitrogen species (RONS) accelerates
the development of inflammatory bowel disease (IBD) and destroys the mucosa and its …

Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …

N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …

[HTML][HTML] Sulfasalazine-loaded nanoparticles for efficient inflammatory bowel disease therapy via ROS-scavenging strategy

S Lin, H Zhao, C Xu, P Zhang, X Mei, D Jiang - Materials & Design, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a life-threatening organ dysfunction amplified by
complex interactions between genetic, environmental, and immune factors. Sulfasalazine …