Celecoxib Inhibits Hepatocellular Carcinoma Cell Growth and Migration by Targeting PNO1 -
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Epstein-Barr virus infection is closely related to the occurrence and development of a variety
of malignant tumors. Tumor immunotherapy has been combined with modern biological high …

The resurgence of cancer immunotherapy stems from an improved understanding of the
tumor microenvironment. The PD-1/PD-L1 axis is of particular interest, in light of promising …

Abstract PD-1/PD-L1 immune checkpoint blockade therapy has become an effective method
for the treatment of cancers in the clinic. It has great clinical advantages and therapeutic …

Simple Summary Immune checkpoint blockade targeting PD-1/PD-L1 has a promising
therapeutic efficacy in different tumors, but a significant percentage of patients cannot benefit …

One of the major breakthroughs in oncology in the past decade has been the research and
development of immune checkpoint inhibitors. Since the discovery of the PD-1/PD-L1 axis …

Abstract Cyclooxygenase-2 (COX-2) is an enzyme that plays an important role in the
production of prostaglandins. Numerous studies have demonstrated increased levels of …

Abstract Purpose: Disruption of PD-L1/cytotoxic T-cell PD-1 signaling by immune checkpoint
inhibitors improves survival in cancer patients. This study sought to identify changes in …

Purpose: Blocking the immunosuppressive PD-1/PD-L1 pathway has antitumor activity in
multiple cancer types, and PD-L1 expression on tumor cells and infiltrating myeloid cells …

The current study reveals the clinicopathological association of PD-L1 in Hong Kong
esophageal squamous cell carcinoma (ESCC) patients and the differential regulation of PD …