Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe

BB Aggarwal, RV Vijayalekshmi, B Sung - Clinical cancer research, 2009 - AACR
Chronic infections, obesity, alcohol, tobacco, radiation, environmental pollutants, and high-
calorie diet have been recognized as major risk factors for the most common types of cancer …

The role of inflammation in mouse pulmonary neoplasia

AK Bauer, EA Rondini - Veterinary pathology, 2009 - journals.sagepub.com
Inflammation is a risk factor for the development of many types of neoplasia, including skin,
colon, gastric, and mammary cancers, among others. Chronic pulmonary diseases, such as …

Emerging avenues linking inflammation and cancer

JK Kundu, YJ Surh - Free Radical Biology and Medicine, 2012 - Elsevier
The role of inflammation in carcinogenesis has been extensively investigated and well
documented. Many biochemical processes that are altered during chronic inflammation …

Lineage factors and differentiation states in lung cancer progression

WKC Cheung, DX Nguyen - Oncogene, 2015 - nature.com
Lung cancer encompasses a heterogeneous group of malignancies. Here we discuss how
the remarkable diversity of major lung cancer subtypes is manifested in their transforming …

Inflammation fuels tumor progress and metastasis

J Liu, P Charles Lin, BP Zhou - Current pharmaceutical design, 2015 - ingentaconnect.com
Inflammation is a beneficial response that can remove pathogens, repair injured tissue and
restore homeostasis to damaged tissues and organs. However, increasing evidence …

Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer

G Lee, TC Walser, SM Dubinett - Current opinion in pulmonary …, 2009 - journals.lww.com
The relationships between inflammation, airflow obstruction, and lung cancer are complex.
Deregulated inflammation is complicit in the pathogenesis of chronic obstructive pulmonary …

[HTML][HTML] Old and new players of inflammation and their relationship with cancer development

R Chavez-Dominguez, M Perez-Medina… - Frontiers in …, 2021 - frontiersin.org
Pathogens or genotoxic agents continuously affect the human body. Acute inflammatory
reaction induced by a non-sterile or sterile environment is triggered for the efficient …

Chronic inflammation and cancer; the two sides of a coin

Q Fernandes, VP Inchakalody, T Bedhiafi, S Mestiri… - Life Sciences, 2023 - Elsevier
The correlation between chronic inflammation and cancer was initially identified in the 19th
century. Biomolecules like interleukins, chemokines, tumor necrosis factors, growth factors …

Inflammation, microenvironment, and the immune system in cancer progression

A Keibel, V Singh, MC Sharma - Current pharmaceutical design, 2009 - ingentaconnect.com
Since Virchow first proposed in 1863 that tumors could originate from sites of chronic
inflammation, it has been well established that chronic inflammation both contributes to …

Inflammation and oncogenesis: a vicious connection

SI Grivennikov, M Karin - Current opinion in genetics & development, 2010 - Elsevier
Epidemiological and experimental data suggest a close connection between inflammation
and tumorigenesis. Solid tumors are typically infiltrated with immune cells and inflammation …