Microenvironment responsive pod-structured astaxanthin nanocarrier for ameliorating inflammatory bowel disease
J Wang, Y Chen, L Han, S Xia, X Zhang, P Xue… - Chinese Chemical …, 2024 - Elsevier
Anti-inflammatory drugs targeting inflammatory bowel disease (IBD) have attracted
considerable attention but still face low therapeutic outcomes and frequent side effects …
considerable attention but still face low therapeutic outcomes and frequent side effects …
Orally deliverable sequence-targeted astaxanthin nanoparticles for colitis alleviation
Y Chen, W Su, S Tie, W Cui, X Yu, L Zhang, Z Hua… - Biomaterials, 2023 - Elsevier
Orally targeted strategy of anti-inflammatory agents has attracted tremendous attention for
reducing highly health-care costs and enhancing the intervention efficiency of ulcerative …
reducing highly health-care costs and enhancing the intervention efficiency of ulcerative …
Oral Delivery of Astaxanthin via Carboxymethyl Chitosan-Modified Nanoparticles for Ulcerative Colitis Treatment
W Zhang, X Zhang, X Lv, A Qu, W Liang, L Wang… - Molecules, 2024 - mdpi.com
The oral delivery strategy of natural anti-oxidant and anti-inflammatory agents has attracted
great attention to improve the effectiveness of ulcerative colitis (UC) treatment. Herein, we …
great attention to improve the effectiveness of ulcerative colitis (UC) treatment. Herein, we …
Bi-functional astaxanthin macromolecular nanocarriers to alleviate dextran sodium sulfate-induced inflammatory bowel disease
Dextran sulfate sodium is one of the important members in the field of polysaccharide
biotechnology, which can induce inflammatory bowel disease (IBD) in the gastrointestinal …
biotechnology, which can induce inflammatory bowel disease (IBD) in the gastrointestinal …
A smart cauliflower-like carrier for astaxanthin delivery to relieve colon inflammation
As a fat-soluble carotenoid, astaxanthin has excellent antioxidant and anti-inflammation
biological activities, but its poor biocompatibility and low stability limit application of …
biological activities, but its poor biocompatibility and low stability limit application of …
ROS-triggered self-disintegrating and pH-responsive astaxanthin nanoparticles for regulating the intestinal barrier and colitis
Smart delivery systems with stimuli-responsive capability are able to improve the
bioaccessibility through increasing the solubility, physicochemical stability and …
bioaccessibility through increasing the solubility, physicochemical stability and …
Preparation of cellulose-based nanoparticles via electrostatic self-assembly for the pH-responsive delivery of astaxanthin
M Gan, A Cao, L Cai, X Xiang, J Li, Q Luan - Food Chemistry, 2024 - Elsevier
Oral administration of astaxanthin (AST), a potent antioxidant, is limited owing to its low
solubility, physicochemical stability, and bioavailability. This study developed pH-responsive …
solubility, physicochemical stability, and bioavailability. This study developed pH-responsive …
Readily Available Oral Prebiotic Protein Reactive Oxygen Species Nanoscavengers for Synergistic Therapy of Inflammation and Fibrosis in Inflammatory Bowel …
Y Yu, D Yang, B Lin, L Zhu, C Li, X Li - ACS nano, 2024 - ACS Publications
A significant gap exists in the demand for safe and effective drugs for inflammatory bowel
disease (IBD), and its associated intestinal fibrosis. As oxidative stress plays a central role in …
disease (IBD), and its associated intestinal fibrosis. As oxidative stress plays a central role in …
ROS-responsive carboxymethyl chitosan nanoparticles loaded with astaxanthin for alleviating oxidative damage in intestinal cells
X Yu, Y Chen, M Tan - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
The controlled release of antioxidant substances at the intestinal oxidative damage site is
crucial for alleviating intestine-related diseases. Herein, the novel ROS-responsive carrier …
crucial for alleviating intestine-related diseases. Herein, the novel ROS-responsive carrier …
Green fabrication of ovalbumin nanoparticles as natural polyphenol carriers for ulcerative colitis therapy
S Gou, Q Chen, Y Liu, L Zeng, H Song… - ACS Sustainable …, 2018 - ACS Publications
Nanoparticles (NPs) have the capacity to improve the bioactivity and bioavailability of anti-
inflammatory drugs. Here, a green drug nanocarrier based on ovalbumin (OVA) was facilely …
inflammatory drugs. Here, a green drug nanocarrier based on ovalbumin (OVA) was facilely …