Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of …

MK Hart, TJ Palker, TJ Matthews… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
We have previously described a synthetic peptide (T1-SP10) derived from two
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …
被引用次数：112 相关文章 所有 7 个版本

Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes.

TJ Palker, TJ Matthews, A Langlois… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
In previous studies, we have used antisera raised to envelope (env)-gene-encoded
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …
被引用次数：187 相关文章 所有 5 个版本
[PDF] archive.org

Priming with T helper cell epitope peptides enhances the antibody response to the envelope glycoprotein of HIV-1 in primates.

A Hosmalin, PL Nara, M Zweig, NW Lerche… - … (Baltimore, Md.: 1950 …, 1991 - journals.aai.org
The induction of a memory immune response to HIV, mediated by any kind of effector
mechanism, requires the induction of T cell help. In previous studies performed in different …
被引用次数：43 相关文章 所有 10 个版本
[PDF] pnas.org

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

TJ Palker, ME Clark, AJ Langlois… - Proceedings of the …, 1988 - National Acad Sciences
A synthetic peptide (SP-10-IIIB) with an amino acid sequence [Cys-Thr-Arg-Pro-Asn-Asn-
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …
被引用次数：669 相关文章 所有 11 个版本
[PDF] researchgate.net

A synthetic peptide from the first conserved region in the envelope protein gp160 is a strong T-cell epitope in HIV-infected chimpanzees and humans

PN Nehete, SJ Schapiro, PC Johnson, KK Murthy… - Viral …, 1998 - liebertpub.com
We reported earlier that synthetic peptides corresponding to highly conserved regions in the
envelope protein gp160 of the human immunodeficiency virus type 1 (HIV-1), in particular an …
被引用次数：27 相关文章 所有 5 个版本
[PDF] asm.org

B-and T-lymphocyte responses to an immunodominant epitope of human immunodeficiency virus

RD Schrier, JW Gnann Jr, AJ Langlois… - Journal of …, 1988 - Am Soc Microbiol
Using synthetic peptides, we characterized the B-lymphocyte (antibody) and T-lymphocyte
(proliferation) responses to an immunodominant epitope of human immunodeficiency virus …
被引用次数：104 相关文章 所有 10 个版本
[PDF] pnas.org

Immunizations of monkeys with synthetic peptides disclose conserved areas on gp120 of human immunodeficiency virus type 1 associated with cross-neutralizing …

A Vahlne, P Horal, K Eriksson… - … of The National …, 1991 - National Acad Sciences
Site-directed immunization was employed to identify sites on the envelope glycoprotein
gp120 for antibody-mediated neutralization of human immunodeficiency virus type 1 (HIV-1) …
被引用次数：33 相关文章 所有 10 个版本
[PDF] pnas.org

Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native …

KB Cease, H Margalit, JL Cornette… - Proceedings of the …, 1987 - National Acad Sciences
Much effort has been devoted to the analysis of antibodies to acquired immunodeficiency
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …
被引用次数：225 相关文章 所有 12 个版本
[PDF] researchgate.net

Induction of HIVMN neutralizing antibodies in primates using a prime-boost regimen of hybrid synthetic gp120 envelope peptides.

BF Haynes, JV Torres, AJ Langlois… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
We have tested synthetic peptides composed of Th (T1) and V3 loop B cell neutralizing
determinants [SP10 MN (A)] of HIVMN gp120 and the fusogenic (F) domain of gp41 as …
被引用次数：59 相关文章 所有 10 个版本
[PDF] archive.org

A universal T cell epitope-containing peptide from hepatitis B surface antigen can enhance antibody specific for HIV gp120.

JL Greenstein, VC Schad, WH Goodwin… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
Peptide-based vaccines that directly target T cell or B cell epitopes may have significant
advantages over conventional vaccines. Further, synthetic chimeric peptides that combine …
被引用次数：53 相关文章 所有 7 个版本