Riboflavin, a water-soluble vitamin also known as vitamin B2, is essential for normal cellular
functions. Riboflavin transporters play important roles in its homeostasis. Recently, three …

Absorption of riboflavin is mediated by transporter (s). However, a mammalian riboflavin
transporter has yet to be identified. In the present study, the novel human and rat riboflavin …

We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

We have newly identified rat riboflavin transporter 2 (rRFT2) and its human orthologue
(hRFT2), and carried out detailed functional characterization of rRFT2. The mRNA of rRFT2 …

Riboflavin transporter deficiency (RTD) is a rare neurological condition that encompasses
the Brown‐Vialetto‐Van Laere and Fazio‐Londe syndromes since the discovery of …

Riboflavin transporter (RFT) 2 has recently been identified as a transporter that may be,
mainly based on the functional characteristics of its rat ortholog (rRFT2), involved in the …

Introduction Riboflavin (vitamin B2) is absorbed in the small intestine by the human
riboflavin transporters RFVT1 and RFVT3. A third riboflavin transporter (RFVT2) is …

The water-soluble vitamin B2 (riboflavin, RF) is an essential micronutrient for normal cell
function and survival. Recent studies have identified a role for the human riboflavin …

Abstract Brown-Vialetto-Van Laere syndrome (BVVLS [MIM 211530]) is a rare neurological
disorder characterized by infancy onset sensorineural deafness and ponto-bulbar palsy …

Transport of riboflavin (RF) across both the brush border membrane (BBM) and basolateral
membrane (BLM) of the polarized enterocyte occurs via specific carrier-mediated …