Towards enabling cardiac digital twins of myocardial infarction using deep computational models for inverse inference

L Li, J Camps, Z Wang, M Beetz… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
Cardiac digital twins (CDTs) have the potential to offer individualized evaluation of cardiac
function in a non-invasive manner, making them a promising approach for personalized …

[HTML][HTML] Inference of ventricular activation properties from non-invasive electrocardiography

J Camps, B Lawson, C Drovandi, A Minchole… - Medical Image …, 2021 - Elsevier
The realisation of precision cardiology requires novel techniques for the non-invasive
characterisation of individual patients' cardiac function to inform therapeutic and diagnostic …

Deep computational model for the inference of ventricular activation properties

L Li, J Camps, A Banerjee, M Beetz… - … Workshop on Statistical …, 2022 - Springer
Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …

[HTML][HTML] A framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs

K Gillette, MAF Gsell, AJ Prassl, E Karabelas… - Medical image …, 2021 - Elsevier
Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …

Cardiac Digital Twin Pipeline for Virtual Therapy Evaluation

J Camps, ZJ Wang, R Doste, M Holmes… - arXiv preprint arXiv …, 2024 - arxiv.org
Cardiac digital twins are computational tools capturing key functional and anatomical
characteristics of patient hearts for investigating disease phenotypes and predicting …

Quantifying variabilities in cardiac digital twin models of the electrocardiogram

E Zappon, MAF Gsell, K Gillette, G Plank - arXiv preprint arXiv:2407.17146, 2024 - arxiv.org
CDT of human cardiac EP are digital replicas of patient hearts that match like-for-like clinical
observations. The ECG, as the most prevalent non-invasive observation of cardiac …

[HTML][HTML] Harnessing 12-lead ECG and MRI data to personalise repolarisation profiles in cardiac digital twin models for enhanced virtual drug testing

J Camps, ZJ Wang, R Doste, LA Berg, M Holmes… - Medical Image …, 2024 - Elsevier
Cardiac digital twins are computational tools capturing key functional and anatomical
characteristics of patient hearts for investigating disease phenotypes and predicting …

HDL: Hybrid deep learning for the synthesis of myocardial velocity maps in digital twins for cardiac analysis

X Xing, J Del Ser, Y Wu, Y Li, J Xia, L Xu… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
Synthetic digital twins based on medical data accelerate the acquisition, labelling and
decision making procedure in digital healthcare. A core part of digital healthcare twins is …

Parameter subset reduction for imaging-based digital twin generation of patients with left ventricular mechanical discoordination

T Koopsen, N van Osta, T van Loon, R Meiburg… - BioMedical Engineering …, 2024 - Springer
Background Integration of a patient's non-invasive imaging data in a digital twin (DT) of the
heart can provide valuable insight into the myocardial disease substrates underlying left …

Deep learning-based emulation of human cardiac activation sequences

A Bertrand, J Camps, V Grau, B Rodriguez - International Conference on …, 2023 - Springer
The vision of digital twins for precision cardiology is to combine expert knowledge and data
of patients' cardiac pathophysiology with advanced computational methods, in order to …