Cilostazol is practically insoluble in water and thus results in poor bioavailability. Only a few
approaches have been reported for improving the bioavailability of cilostazol. Solid …

Objective Cilostazol is a Biopharmaceutical Classification System class II drug with low
solubility and high permeability, so its oral absorption is variable and incomplete. The aim of …

The study was designed to investigate the effect of cyclodextrins (CDs) on the solubility,
dissolution rate, and bioavailability of cilostazol by forming inclusion complexes. Natural …

Purpose: The aim of this study was to develop cilostazol (CLT) nanocrystals intended to
improve its dissolution rate and enhance its bioavailability. Methods: In this study, CLT …

The aim of this research was to compare three different types of cilostazol-loaded solid
dispersion system including solvent-evaporated, solvent-wetted and surface-attached solid …

The aim of this new work was to improve the dissolution rate of poorly water-soluble
cilostazol (CLT) by adsorbing dissolved drug molecules onto the surface of undissolved …

A simple, selective, precise and stability-indicating high-performance liquid-
chromatographic method of analysis of cilostazol in pharmaceutical dosage form was …

A growing number of poorly water-soluble drug have been discovered, but the poor
bioavailability is a critical problem. In this study, physical properties and dissolution profiles …

The aim of the study was to formulate cilostazol containing nanosuspension by top-down
wet milling method in order to increase the in vitro solubility and dissolution rate of this …

The purpose of the present study was to investigate oral bioavailability of an immediate
release tablet containing wet-milled crystals of a poorly water-soluble drug, cilostazol, and to …