Lupus nephritis (LN) occurs in 50%–60% of patients with childhood-onset systemic lupus
erythematosus (cSLE), leading to significant morbidity. Timely recognition of renal …

Childhood-onset systemic lupus erythematosus (cSLE) is a rare, multisystem and potentially
life-threatening autoimmune disorder with significant associated morbidity. Evidence-based …

Objectives To develop recommendations for the management of adult and paediatric lupus
nephritis (LN). Methods The available evidence was systematically reviewed using the …

Lupus nephritis (LN) is a life-threatening manifestation of systemic lupus erythematosus
(SLE) and is more common in children than adults. The epidemiology and management of …

The care of children with lupus nephritis (LN) has changed dramatically over the past 50 y.
The majority of patients with childhood-onset systemic lupus erythematosus (cSLE) develop …

In the past years, many (randomized) trials have been performed comparing the treatment
strategies for lupus nephritis. In 2012, these data were incorporated in six different …

In systemic lupus erythematosus renal involvement is more frequent in children than in
adults. Overall, 60-80% of children with systemic lupus erythematosus have urinary or renal …

Childhood-onset systemic lupus erythematosus (cSLE) is a severe multisystem autoimmune
disease. Renal involvement occurs in the majority of cSLE patients and is often fatal. Renal …

Despite the negative outcome of recent trials there is growing evidence that there are
increasing opportunities in patients with lupus nephritis to offer treatments tailored to the …

There is still a significant morbidity and mortality associated with childhood‐onset systemic
lupus erythematosus (SLE), despite an increasing armamentarium of immunosuppressive …