A Bioengineered Nisin Derivative to Control Biofilms of Staphylococcus pseudintermedius
Antibiotic resistance and the shortage of novel antimicrobials are among the biggest
challenges facing society. One of the major factors contributing to resistance is the use of …
challenges facing society. One of the major factors contributing to resistance is the use of …
Bio-Engineered Nisin with Increased Anti-Staphylococcus and Selectively Reduced Anti-Lactococcus Activity for Treatment of Bovine Mastitis
Bovine mastitis is a significant economic burden for dairy enterprises, responsible for
premature culling, prophylactic and therapeutic antibiotic use, reduced milk production and …
premature culling, prophylactic and therapeutic antibiotic use, reduced milk production and …
In Vitro Activities of Nisin and Nisin Derivatives Alone and In Combination with Antibiotics against Staphylococcus Biofilms
The development and spread of pathogenic bacteria that are resistant to the existing catalog
of antibiotics is a major public health threat. Biofilms are complex, sessile communities of …
of antibiotics is a major public health threat. Biofilms are complex, sessile communities of …
Studies with bioengineered Nisin peptides highlight the broad‐spectrum potency of Nisin V
Nisin A is the most thoroughly investigated member of the lantibiotic family of antimicrobial
peptides. In addition to a long history of safe use as a food antimicrobial, its activity against …
peptides. In addition to a long history of safe use as a food antimicrobial, its activity against …
A bioengineered nisin derivative to control Streptococcus uberis biofilms
Antimicrobial peptides are evolving as novel therapeutic options against the increasing
problem of multidrug-resistant microorganisms, and nisin is one such avenue. However …
problem of multidrug-resistant microorganisms, and nisin is one such avenue. However …
Nisin variants generated by protein engineering and their properties
Y Zheng, Y Du, Z Qiu, Z Liu, J Qiao, Y Li, Q Caiyin - Bioengineering, 2022 - mdpi.com
Nisin, a typical lantibiotic, has robust antimicrobial activity combined with limited cytotoxicity,
and the development of resistance to it is slow. These properties make nisin a promising …
and the development of resistance to it is slow. These properties make nisin a promising …
The generation of nisin variants with enhanced activity against specific gram‐positive pathogens
Nisin is the prototype of the lantibiotic group of antimicrobial peptides. It exhibits broad
spectrum inhibition of Gram‐positive bacteria including important food pathogens and …
spectrum inhibition of Gram‐positive bacteria including important food pathogens and …
Bioengineered nisin A derivatives with enhanced activity against both Gram positive and Gram negative pathogens
Nisin is a bacteriocin widely utilized in more than 50 countries as a safe and natural
antibacterial food preservative. It is the most extensively studied bacteriocin, having …
antibacterial food preservative. It is the most extensively studied bacteriocin, having …
Bioengineered Nisin Derivative M17Q Has Enhanced Activity against Staphylococcus epidermidis
Staphylococcus epidermidis is frequently implicated in medical device-related infections. As
a result of this, novel approaches for control of this opportunistic pathogen are required. We …
a result of this, novel approaches for control of this opportunistic pathogen are required. We …
A novel bioengineered derivative of nisin displays enhanced antimicrobial activity against clinical Streptococcus agalactiae isolates
Objectives Streptococcus agalactiae is the leading cause of neonatal disease worldwide,
and infections caused by this opportunistic pathogen are becoming increasingly more …
and infections caused by this opportunistic pathogen are becoming increasingly more …