Prognostic Significance and Clinicopathological Associations of COX‐2 SNP in Patients with Nonsmall Cell Lung Cancer

PP Grimminger, J Stöhlmacher… - Journal of …, 2009 - Wiley Online Library
Background. To further improve the screening, diagnosis, and therapy of patients with
nonsmall cell lung cancer (NSCLC) additional diagnostic tools are urgently needed. Gene …

[HTML][HTML] Clinical value of cyclooxygenase-2 expression in human breast carcinoma

JH Ahn, SB Kim, SH Ahn, GY Gong… - … : Official Journal of …, 2004 - synapse.koreamed.org
Purpose To determine whether COX-2 expression is associated with clinicopathological
parameters, including c-erb-B2 overexpression and angiogenesis, and the disease-free …

Cyclooxygenase-2 expression is not a marker of poor survival in lung cancer

HM Turk, C Camci, A Sevinc… - Asian Pacific Journal …, 2012 - koreascience.kr
Objective: Cyclooxygenase-2 (COX-2) has been claimed to play role in carcinogenesis and
be related to a bad prognosis in tumours. The aim of this study was to investigate the …

[HTML][HTML] Relationship between epidermal growth factor receptor (EGFR) mutation and serum cyclooxygenase-2 Level, and the synergistic effect of celecoxib and …

N Li, H Li, F Su, J Li, X Ma, P Gong - International journal of clinical …, 2015 - ncbi.nlm.nih.gov
Epidermal growth factor receptor (EGFR) mutations occur mostly in patients with lung
adenocarcinoma; such patients are also more likely to express cyclooxygenase-2 (COX-2) …

Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: potential targets for chemoprevention and systemic …

CM Richardson, RA Sharma, G Cox, KJ O'Byrne - Lung cancer, 2003 - Elsevier
The epidermal growth factor receptor (EGFR) is part of a family of plasma membrane
receptor tyrosine kinases that control many important cellular functions, from growth and …

Significance of cyclooxygenase-2 in prognosis, targeted therapy and chemoprevention of NSCLC

JM Lee, JT Mao, K Krysan, SM Dubinett - Future Oncology, 2007 - Taylor & Francis
Evaluation of: Tsubochi H, Nobuyuki S, Hiyama M et al.: Combined analysis of
cyclooxygenase-2 expression with p53 and Ki-67 in nonsmall cell lung cancer. Ann. Thorac …

Interaction of cyclooxygenase 2 genotype and smoking habit in Taiwanese lung cancer patients

CJ Liu, TC Hsia, RF Wang, CW Tsai, CC Chu… - Anticancer …, 2010 - ar.iiarjournals.org
Aim: The aim of this study was to evaluate the association and interaction of genotypic
polymorphisms in the cyclooxygenase 2 (Cox-2) gene with smoking habits with lung cancer …

Chemotherapy Induces the Expression of Cyclooxygenase-2 in Non–Small Cell Lung Cancer

NK Altorki, JL Port, F Zhang, D Golijanin, HT Thaler… - Clinical cancer …, 2005 - AACR
Purpose: To determine the effect of taxane-based chemotherapy on intratumoral levels of
cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2) in patients with non–small cell …

COX-2 and its inhibition as a molecular target in the prevention and treatment of lung cancer

Z Liao, L Milas - Expert review of anticancer therapy, 2004 - Taylor & Francis
Lung cancer is the leading cause of cancer death in the USA. Conventional therapy using
chemotherapy, radiation therapy, and a combination of the two, has yielded modest …

[HTML][HTML] Association between COX-2 polymorphisms and lung cancer risk

W Wang, X Fan, Y Zhang, Y Yang… - Medical Science Monitor …, 2015 - ncbi.nlm.nih.gov
Background Multiple relevant risk factors for lung cancer have been reported in different
populations, but results of previous studies were not consistent. Therefore, a meta-analysis …