Since Virchow first proposed in 1863 that tumors could originate from sites of chronic
inflammation, it has been well established that chronic inflammation both contributes to …

State of the Art: Mounting evidence indicates a link between inflammation and cancer.
However, the molecular mechanism (s) remains unclear. Indeed, although preclinical and …

During carcinogenesis, advanced tumors are surrounded by both stromal and immune cells,
which support tumor development. In addition, inflammation and angiogenesis are …

Historically, the link between chronic inflammation and cancer has long been speculated.
Only more recently, pre-clinical and epidemiologic data as well as clinical evidence all point …

Inflammation has long been thought to contribute to the development of cancer; however
there is also clear evidence that the immune system can recognize and eliminate cancer …

Inflammatory mediators in tumor microenvironment influence cancer occurrence, growth and
metastasis through complex signaling networks. Excessive inflammation is closely …

The link with chronic inflammation and cancer has been recognized for certain cancers for
several decades. However, only recently has the biology of chronic inflammation begun to …

Central to the development of cancer are genetic changes that endow these “cancer cells”
with many of the hallmarks of cancer, such as self-sufficient growth and resistance to anti …

Among the most extensively researched processes in the development and treatment of
cancer is inflammatory condition. Although acute inflammation is essential for the wound …

Angiogenesis, the formation of new blood vessels, as well as inflammation with massive
infiltration of leukocytes are hallmarks of various tumor entities. Various epidemiological …