The majority of research within reproductive and gynecologic health, or investigating ART, is
observational in design. One of the most critical challenges for observational studies is …

Description of the process by which someone else could obtain the data and computing
code required to replicate the results reported in your submission (or explanation why data …

Systematic reviews and meta‐analyses are essential for drawing conclusions regarding
etiologic associations between exposures or interventions and health outcomes …

A mediator is a factor that occurs after the exposure of interest, precedes the outcome of
interest (ie between the exposure and the outcome) and is associated with both the …

The cross-sectional study design is sometimes avoided by researchers or considered an
undesired methodology. Possible reasons include incomplete understanding of the …

This article challenges the “tyranny of P-value” and promote more valuable and applicable
interpretations of the results of research on health care delivery. We provide here solid …

Much of the published medical research is apparently flawed, cannot be replicated and/or
has limited or no utility. This article presents an overview of the current landscape of …

Randomized controlled trials provide the most valid basis for comparing alternative
treatment modalities. Unfortunately, the quality of many such trials has not been as high as …

Although randomized controlled trials provide the highest level of evidence for causation,
many clinical issues cannot be addressed using experimental study design. Examples that …

Observational studies, when done well, enable inferences of causal associations. However,
most observational studies cannot achieve inferences regarding causality, because of the …