Background: Cilostazol is an anti-platelets drug with considerable antithrombotic effects in
vivo. Therefore, it is widely used by elderly patients. However, it suffers from poor …

The aim of the study was to formulate cilostazol containing nanosuspension by top-down
wet milling method in order to increase the in vitro solubility and dissolution rate of this …

A growing number of poorly water-soluble drug have been discovered, but the poor
bioavailability is a critical problem. In this study, physical properties and dissolution profiles …

Cilostazol was selected as poorly-soluble model drug to investigate the impact of the
manufacturing method on the excipient functionality of PEG4000 at various levels. Powder …

The aim of this new work was to improve the dissolution rate of poorly water-soluble
cilostazol (CLT) by adsorbing dissolved drug molecules onto the surface of undissolved …

In present investigation liquisolid compact technique is investigated as a tool for enhanced
dissolution of poorly water-soluble drug Ketoconazole. The liquisolid tablets were …

Cilostazol is practically insoluble in water and thus results in poor bioavailability. Only a few
approaches have been reported for improving the bioavailability of cilostazol. Solid …

The present study was designed to formulate and develop fast disintegrating pellets of
poorly soluble model drug (cilostazol) by reducing the proportion of micro-crystalline …

Improvement in dissolution of the drugs having poor solubility is a challenge in
pharmaceutical industry. Micronization is one technique, employed for dissolution …

Purpose: The aim of this study was to develop cilostazol (CLT) nanocrystals intended to
improve its dissolution rate and enhance its bioavailability. Methods: In this study, CLT …