Phase2 study of bevacizumab with carboplatin–paclitaxel for non-small cell lung cancer with malignant pleural effusion

M Tamiya, A Tamiya, T Yamadori, K Nakao, K Asami… - Medical oncology, 2013 - Springer
Vascular endothelial growth factor (VEGF) is involved in non-small cell lung cancer
(NSCLC) with malignant pleural effusion (MPE), but little is known regarding the efficacy of …

Phase 2 study of bevacizumab plus carboplatin/nab-paclitaxel followed by bevacizumab plus nab‐paclitaxel for non‐squamous non‐small cell lung cancer with …

M Tamiya, A Tamiya, H Suzuki, Y Taniguchi… - Investigational new …, 2021 - Springer
Objectives Vascular endothelial growth factor plays an important role in the pathogenesis of
malignant pleural effusion (MPE). We previously showed the efficacy of bevacizumab (Bev) …

A phase II study of bevacizumab with carboplatin-pemetrexed in non-squamous non-small cell lung carcinoma patients with malignant pleural effusions: North East …

K Usui, S Sugawara, M Nishitsuji, Y Fujita, A Inoue… - Lung cancer, 2016 - Elsevier
Background Vascular endothelial growth factor (VEGF) plays a pivotal role in the
pathogenesis of malignant pleural effusion (MPE). Here, a multicenter phase II trial to …

Bevacizumab plus chemotherapy for advanced non-squamous non-small-cell lung cancer with malignant pleural effusion

K Kitamura, K Kubota, M Ando, S Takahashi… - Cancer chemotherapy …, 2013 - Springer
Purpose The presence of malignant pleural effusion (MPE) indicates a poorer prognosis for
patients with non-small-cell lung cancer (NSCLC) and impairs their quality of life. Because …

Vascular Endothelial Growth Factor in Plasma and Pleural Effusion Is a Biomarker for Outcome After Bevacizumab plus Carboplatin–Paclitaxel Treatment for Non …

M Tamiya, A Tamiya, T Yasue, K Nakao… - Anticancer …, 2016 - ar.iiarjournals.org
Aim: Malignant effusion is associated with high serum and plasma levels of vascular
endothelial growth factor (VEGF). There are no biomarkers of outcome for bevacizumab …

[HTML][HTML] Intrapleural combination therapy with bevacizumab and cisplatin for non-small cell lung cancer‑mediated malignant pleural effusion

N Du, X Li, F Li, H Zhao, Z Fan, J Ma… - Oncology …, 2013 - spandidos-publications.com
Malignant pleural effusion (MPE) is a common complication of advanced non-small cell lung
cancer (NSCLC). Bevacizumab, a humanized monoclonal antibody against vascular …

[HTML][HTML] Response to bevacizumab combination chemotherapy of malignant pleural effusions associated with non‑squamous non-small‑cell lung cancer

K Masago, D Fujimoto, S Fujita… - Molecular and …, 2015 - spandidos-publications.com
Malignant pleural effusion (MPE) is a common complication of lung cancer with devastating
consequences. Since vascular endothelial growth factor (VEGF) has been implicated in …

Bevacizumab plus chemotherapy in nonsquamous non‐small cell lung cancer patients with malignant pleural effusion uncontrolled by tube drainage or pleurodesis: a …

R Noro, K Kobayashi, J Usuki, M Yomota… - Thoracic …, 2020 - Wiley Online Library
Background Pleurodesis is the standard of care for non‐small cell lung cancer (NSCLC)
patients with symptomatic malignant pleural effusion (MPE). However, there is no standard …

Outcomes of bevacizumab combined with chemotherapy in lung adenocarcinoma‐induced malignant pleural effusion

H Tao, Q Meng, M Li, L Shi, J Tang, Z Liu - Thoracic Cancer, 2018 - Wiley Online Library
Background VEGF is critical in the pathogenesis of malignant pleural effusion (MPE). To
understand the clinical benefits of antiangiogenic agents, the efficacy of chemotherapy …

A randomized clinical study to compare intrapleural infusion with intravenous infusion of bevacizumab in the management of malignant pleural effusion in patients with …

K Nie, Z Zhang, Y You, X Zhuang, C Zhang… - Thoracic Cancer, 2020 - Wiley Online Library
Background To compare the efficiency and toxicity of bevacizumab by intrapleural or
intravenous infusion in the management of malignant pleural effusion in patients with non …