Concepts and methods to access novel antibiotics from actinomycetes
Actinomycetes have been proven to be an excellent source of secondary metabolites for
more than half a century. Exhibiting various bioactivities, they provide valuable approved …
more than half a century. Exhibiting various bioactivities, they provide valuable approved …
Mining actinomycetes for novel antibiotics in the omics era: are we ready to exploit this new paradigm?
O Genilloud - Antibiotics, 2018 - mdpi.com
The current spread of multi-drug resistance in a number of key pathogens and the lack of
therapeutic solutions in development to address most of the emerging infections in the clinic …
therapeutic solutions in development to address most of the emerging infections in the clinic …
Actinomycetes: still a source of novel antibiotics
O Genilloud - Natural product reports, 2017 - pubs.rsc.org
Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …
sources for the discovery of new antibiotics with an important number of drugs and analogs …
New dimensions of research on actinomycetes: quest for next generation antibiotics
Starting with the discovery of streptomycin, the promise of natural products research on
actinomycetes has been captivating researchers and offered an array of life-saving …
actinomycetes has been captivating researchers and offered an array of life-saving …
Renaissance in antibacterial discovery from actinomycetes
RH Baltz - Current opinion in pharmacology, 2008 - Elsevier
The soil actinomycetes have been important sources of antibiotics, but were nearly
abandoned in recent years in favor of high-throughput target-based screening of chemical …
abandoned in recent years in favor of high-throughput target-based screening of chemical …
Renewed interests in the discovery of bioactive actinomycete metabolites driven by emerging technologies
Actinomycetes are prolific sources of bioactive molecules. Traditional workflows including
bacterial isolation, fermentation, metabolite identification and structure elucidation have …
bacterial isolation, fermentation, metabolite identification and structure elucidation have …
Biodiscovery from rare actinomycetes: an eco-taxonomical perspective
DI Kurtböke - Applied microbiology and biotechnology, 2012 - Springer
Microbial natural products, in particular, the ones produced by the members of the order
Actinomycetales, will continue to represent an important route to the discovery of novel …
Actinomycetales, will continue to represent an important route to the discovery of novel …
Challenges and advances in genetic manipulation of filamentous actinomycetes–the remarkable producers of specialized metabolites
EM Musiol-Kroll, A Tocchetti, M Sosio… - Natural Product …, 2019 - pubs.rsc.org
Covering: up to February 2019 Actinomycetes are Gram positive bacteria of the phylum
Actinobacteria. These organisms are one of the most important sources of structurally …
Actinobacteria. These organisms are one of the most important sources of structurally …
Genomic basis for natural product biosynthetic diversity in the actinomycetes
M Nett, H Ikeda, BS Moore - Natural product reports, 2009 - pubs.rsc.org
Covering: up to mid-2009 The phylum Actinobacteria hosts diverse high G+ C, Gram-
positive bacteria that have evolved a complex chemical language of natural product …
positive bacteria that have evolved a complex chemical language of natural product …
Uncovering the biodiversity and biosynthetic potentials of rare actinomycetes
Background Antibiotic resistance is on the rise, and new antibiotic research has slowed in
recent years, necessitating the discovery of possibly novel microbial resources capable of …
recent years, necessitating the discovery of possibly novel microbial resources capable of …