Background Metastasis occurs in a series of discrete steps involving invasion, angiogenesis,
lymphovascular space permeation, and establishment of secondary tumors. Malignant …

Malignant Pleural Effusions (MPE) may be useful as a model to study hierarchical
progression of cancer and/or intratumoral heterogeneity. To strengthen the rationale for …

Malignant pleural effusion (MPE) can accompany advanced lung adenocarcinoma. Recent
studies suggest that MPE could contain a heterogeneous subpopulation of cells with stem …

Background Recurrent malignant pleural effusion (MPE) resulting from non‐small‐cell lung
cancer (NSCLC) is easily refractory to conventional therapeutics and lacks predictive …

Lung cancer stem cells are supposed to be the main drivers of tumor initiation, maintenance,
drug resistance, and relapse of the disease. Hence, identification of the cellular and …

Pulmonary adenocarcinoma (PADC) treatment limited efficacy in preventing tumor
progression, often resulting in malignant pleural effusion (MPE). MPE is filled with various …

Malignant pleural effusions (MPEs) are a common manifestation found in patients with lung
cancer. After cytological and histological confirmation of malignancy, talc pleurodesis still …

The presence of leukocyte subpopulations in malignant pleural effusions (MPEs) can have a
different impact on tumor cell proliferation and vascular leakiness, their analysis can help to …

Background Malignant pleural effusion (MPE) has a profound impact on quality of life and
survival in patients with lung cancer. Identification of the factors within the tumor and its …

Background Lung cancer is the leading cause of cancer related deaths and Malignant
Pleural Effusion (MPE) is a frequent complication. Current therapies suffer from lack of …