Whole-animal connectomes of both Caenorhabditis elegans sexes

SJ Cook, TA Jarrell, CA Brittin, Y Wang, AE Bloniarz… - Nature, 2019 - nature.com
Abstract Knowledge of connectivity in the nervous system is essential to understanding its
function. Here we describe connectomes for both adult sexes of the nematode …

Sex-specific pruning of neuronal synapses in Caenorhabditis elegans

M Oren-Suissa, EA Bayer, O Hobert - Nature, 2016 - nature.com
Whether and how neurons that are present in both sexes of the same species can
differentiate in a sexually dimorphic manner is not well understood. A comparison of the …

Glia-derived neurons are required for sex-specific learning in C. elegans

M Sammut, SJ Cook, KCQ Nguyen, T Felton, DH Hall… - Nature, 2015 - nature.com
Sex differences in behaviour extend to cognitive-like processes such as learning, but the
underlying dimorphisms in neural circuit development and organization that generate these …

A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans

EZ Macosko, N Pokala, EH Feinberg, SH Chalasani… - Nature, 2009 - nature.com
Innate social behaviours emerge from neuronal circuits that interpret sensory information on
the basis of an individual's own genotype, sex and experience. The regulated aggregation …

Connectomes across development reveal principles of brain maturation

D Witvliet, B Mulcahy, JK Mitchell, Y Meirovitch… - Nature, 2021 - nature.com
An animal's nervous system changes as its body grows from birth to adulthood and its
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …

[HTML][HTML] Neural sex modifies the function of a C. elegans sensory circuit

KH Lee, DS Portman - Current Biology, 2007 - cell.com
Though sex differences in animal behavior are ubiquitous, their neural and genetic
underpinnings remain poorly understood. In particular, the role of functional differences in …

Sexual Dimorphism and Sex Differences in Caenorhabditis elegans Neuronal Development and Behavior

MM Barr, LR García, DS Portman - Genetics, 2018 - academic.oup.com
As fundamental features of nearly all animal species, sexual dimorphisms and sex
differences have particular relevance for the development and function of the nervous …

The connectome of a decision-making neural network

TA Jarrell, Y Wang, AE Bloniarz, CA Brittin, M Xu… - science, 2012 - science.org
In order to understand the nervous system, it is necessary to know the synaptic connections
between the neurons, yet to date, only the wiring diagram of the adult hermaphrodite of the …

Network control principles predict neuron function in the Caenorhabditis elegans connectome

G Yan, PE Vértes, EK Towlson, YL Chew, DS Walker… - Nature, 2017 - nature.com
Recent studies on the controllability of complex systems offer a powerful mathematical
framework to systematically explore the structure–function relationship in biological, social …

[HTML][HTML] Neural signal propagation atlas of Caenorhabditis elegans

F Randi, AK Sharma, S Dvali, AM Leifer - Nature, 2023 - nature.com
Establishing how neural function emerges from network properties is a fundamental problem
in neuroscience. Here, to better understand the relationship between the structure and the …