Epidemiologic studies suggest that cocaine abuse worsens HIV-1 disease progression.
Increased viral load has been suggested to play a key role for the accelerated HIV disease …

Epidemiologic studies have identified cocaine as a cofactor for development of acquired
immunodeficiency syndrome (AIDS). To evaluate this interaction, human peripheral blood …

Commonly misused substances such as alcohol, cocaine, heroin, methamphetamine, and
opioids suppress immune responses and may impact viral pathogenesis. In recent years …

During the course of human immunodeficiency virus type 1 (HIV-1) disease, the virus has
been shown to effectively escape the immune response with the subsequent establishment …

Background: There is a strong correlation between the use and abuse of illicit drugs and the
spread of Human Immunodeficiency Virus (HIV). It is well established that illicit drugs users …

Recent in vitro and in vivo research has suggested that cocaine has a direct effect on the
pathogenesis of AIDS. These findings are confirmed by epidemiological studies linking the …

From the onset of the HIV/AIDS epidemic, the use of licit and illicit drugs has been
investigated for its potential impact on HIV disease progression. Findings from a large …

Background: This study evaluated the relationship between illicit drug use and HIV-1
disease severity in HIV-1–infected patients enrolled in the DREXELMED HIV/AIDS Genetic …

Background: Little is known about the possible role that smoking crack cocaine has on the
incidence of HIV infection. Given the increasing use of crack cocaine, we sought to examine …

Substance abuse is a major barrier in eradication of the HIV epidemic because it serves as a
powerful cofactor for viral transmission, disease progression, and AIDS-related mortality …