Viruses often subvert antiviral immune responses by taking advantage of inhibitory immune
signaling. We investigated if hantaviruses use this strategy. Hantaviruses cause viral …

Hantavirus can cause hemorrhagic fever with renal syndrome (HFRS) in Eurasia and
hantavirus pulmonary syndrome (HPS) in America, with high mortality and unknown …

Dendritic cells (DCs) play a pivotal role as antigen-presenting cells in the antiviral immune
response. Here we show that Hantaan virus (HTNV), which belongs to the Bunyaviridae …

Immediately after viral infection, innate responses including expression of IFN-α/β and IFN-
stimulated genes (ISGs) are elicited ubiquitously by recruitment of specific pathogen …

Hantaviruses are widespread zoonotic pathogens found around the globe. Depending on
their geographical location, hantaviruses can cause two human syndromes, haemorrhagic …

The innate immune response induced by Hantavirus is responsible for endothelial cell
dysfunction and viral pathogenicity. Recent studies demonstrate that TLR4 expression is …

Hantaan virus (HTNV) infection can cause a severe lethal hemorrhagic fever with renal
syndrome (HFRS) in humans. CD8+ T cells play a critical role in combating HTNV infections …

Hantaviruses infection causing severe emerging diseases with high mortality rates in
humans has become public health concern globally. The potential roles of CD4+ T cells in …

Objective Human hantavirus infections can cause haemorrhagic fever with renal syndrome
(HFRS). The pathogenic mechanisms are not fully understood, nor if they affect the humoral …

Hantavirus infection reduces antiviral defenses, increases regulatory responses, and causes
persistent infection in rodent hosts. To address whether hantaviruses alter the maturation …