Purpose To determine whether COX-2 expression is associated with clinicopathological
parameters, including c-erb-B2 overexpression and angiogenesis, and the disease-free …

Purpose Previous epidemiologic studies have demonstrated that nonsteroidal anti-
inflammatory drugs can reduce the risk of breast cancer, and this possibly happens via …

PURPOSE: This study investigates the COX-2 expression in human primary breast
carcinomas and its relationship with both angiogenesis and the expression of estrogen …

Abstract Purpose: Cyclooxygenase (COX)-2 is overexpressed in breast cancer and may
have a role in regulating tumor growth via effects on angiogenesis, cell proliferation, or …

Objective To investigate the expressions of Cyclooxygenase-2 (COX-2) gene and protein in
breast cancer, and understand its clinical significance. Methods Reverse transcription-PCR …

Objective To study the expression of cyclooxygenase-2 (COX-2) gene in breast cancer and
its clinicopathologic characteristics. Methods With beta-actin gene as reference, the COX-2 …

BACKGROUND/AIMS Cyclooxygenase-2 (COX2) plays an important role in the
development of some human cancers, especially in the development of pulmonary, colon …

Representative tumour sections from 468 patients with invasive breast cancer were
immunostained for cyclooxygenase-2 (COX-2) and evaluated. The relationships between …

Aims: Cyclo-oxygenases 1 and 2 (COX-1 and COX-2) are key enzymes in prostaglandin
biosynthesis. COX-2 is induced by a wide variety of stimuli, and present during inflammation …

Background: Cyclooxygenase-2 (COX-2) overexpression clearly plays an important role in
the pathogenesis of breast cancer. In this study, we analysed the relationship between COX …