Background The use of transcatheter aortic-valve replacement has been shown to reduce
mortality among high-risk patients with aortic stenosis who are not candidates for surgical …

Background The Placement of Aortic Transcatheter Valves (PARTNER) trial showed that
among high-risk patients with aortic stenosis, the 1-year survival rates are similar with …

Background A previous analysis in this trial showed that among patients with severe,
symptomatic aortic stenosis who were at low surgical risk, the rate of the composite end …

Background Although transcatheter aortic-valve replacement (TAVR) is an accepted
alternative to surgery in patients with severe aortic stenosis who are at high surgical risk …

Background Many patients with severe aortic stenosis and coexisting conditions are not
candidates for surgical replacement of the aortic valve. Recently, transcatheter aortic-valve …

Background There are scant data on long-term clinical outcomes and bioprosthetic-valve
function after transcatheter aortic-valve replacement (TAVR) as compared with surgical …

Background Previous trials have shown that among high-risk patients with aortic stenosis,
survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical …

Abstract Background: The CoreValve US Pivotal High Risk Trial was the first randomized
trial to show superior 1-year mortality of transcatheter aortic valve replacement (TAVR) …

Aims Additional randomized clinical trial (RCT) data comparing transcatheter aortic valve
implantation (TAVI) with surgical aortic valve replacement (SAVR) is available, including …

Background: The US pivotal trial for the self-expanding valve found that among patients with
severe aortic stenosis at increased risk for surgery, the 1-year survival rate was 4.9 …