A network pharmacology approach to determine the synergetic mechanisms of herb couple for treating rheumatic arthritis

X Xu, J Bi, L Ping, P Li, F Li - Drug Design, Development and …, 2018 - Taylor & Francis
Purpose The purpose of this study was to investigate the therapeutic mechanism (s) of
Clematis chinensis Osbeck/Notopterygium incisum KC Ting ex HT (CN). Methods A network …

[HTML][HTML] Exploring the active ingredients and potential mechanisms of action of sinomenium acutum in the treatment of rheumatoid arthritis based on systems biology …

N Gong, L Wang, L An, YK Xu - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Objective: To investigate and predict the targets and signaling pathways of sinomenium
acutum (SA) in the treatment of rheumatoid arthritis (RA) through systems biology and …

[HTML][HTML] Evaluating the therapeutic mechanisms of selected active compounds in Cornus officinalis and Paeonia lactiflora in rheumatoid arthritis via network …

Q Li, S Hu, L Huang, J Zhang, G Cao - Frontiers in Pharmacology, 2021 - frontiersin.org
Cornus officinalis Sieb et. Zucc and Paeonia lactiflora Pall. have exhibited favorable
therapeutic effects against rheumatoid arthritis (RA), but the specific mechanisms of their …

A systems pharmacology approach to investigate the mechanisms of action of Semen Strychni and Tripterygium wilfordii Hook F for treatment of rheumatoid arthritis

Y Li, J Wang, Y Xiao, Y Wang, S Chen, Y Yang… - Journal of …, 2015 - Elsevier
Ethnopharmacology relevance The angiogenesis control at the initiation of rheumatoid
arthritis (RA) that mainly blocks the inflammatory cascades expects to attenuate the action of …

[HTML][HTML] Identification of tumor necrosis factor-alpha (TNF-α) inhibitor in rheumatoid arthritis using network pharmacology and molecular docking

LL Bai, H Chen, P Zhou, J Yu - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: This study aimed to investigate the molecular mechanism of Radix Paeoniae
Alba (white peony, WP) in treating immune inflammatory diseases of rheumatoid arthritis …

A Network Pharmacology Study on the Active Ingredients and Potential Targets of Tripterygium wilfordii Hook for Treatment of Rheumatoid Arthritis

W Hu, W Fu, X Wei, Y Yang, C Lu… - … and Alternative Medicine, 2019 - Wiley Online Library
Traditional Chinese medicine has specific effect on some chronic diseases in clinic,
especially in rheumatic diseases. Tripterygium wilfordii Hook (TWH) is a traditional Chinese …

Study on the multitarget mechanism and key active ingredients of herba siegesbeckiae and volatile oil against rheumatoid arthritis based on network pharmacology

X Yang, Y Li, R Lv, H Qian, X Chen… - Evidence‐Based …, 2019 - Wiley Online Library
Background. Herba Siegesbeckiae (HS, Xixiancao in Chinese) is widely used to treat
inflammatory joint diseases such as rheumatoid arthritis (RA) and arthritis, and its molecular …

A Systems Biology‐Based Investigation into the Pharmacological Mechanisms of Wu Tou Tang Acting on Rheumatoid Arthritis by Integrating Network Analysis

Y Zhang, D Wang, S Tan, H Xu, C Liu… - Evidence‐Based …, 2013 - Wiley Online Library
Aim. To investigate pharmacological mechanisms of Wu Tou Tang acting on rheumatoid
arthritis (RA) by integrating network analysis at a system level. Methods and Results. Drug …

Deciphering the Active Ingredients and Molecular Mechanisms of Tripterygium hypoglaucum (Levl.) Hutch against Rheumatoid Arthritis Based on Network …

Y Jiang, M Zhong, F Long… - … Based Complementary and …, 2020 - Wiley Online Library
Tripterygium hypoglaucum (Levl.) Hutch (THH) shows well clinical effect on rheumatoid
arthritis (RA), but the active ingredients and molecular mechanisms remain unclear. This …

Network pharmacology analysis of the pharmacological mechanism of Artemisia lavandulaefolia DC. in rheumatoid arthritis

R Huang, R Li, J Chen, M Lv, X Xu - Phytomedicine, 2023 - Elsevier
Abstract Objective The traditional She medicine is a notable type of traditional Chinese
medicine, which has been applied for a long history despite the lack of sufficient mechanistic …