Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope …

MK Gorny, JY Xu, V Gianakakos… - Proceedings of the …, 1991 - National Acad Sciences
Cell lines secreting IgG1 human monoclonal antibodies (mAb) to the envelope glycoprotein,
gp120, of human immunodeficiency virus (HIV) have been produced by transformation of …

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein.

K Javaherian, AJ Langlois… - Proceedings of the …, 1989 - National Acad Sciences
The principal neutralizing determinant of human immunodeficiency virus type 1 (HIV-1) is
located in the external envelope protein, gp120, and has previously been mapped to a 24 …

HIV-1 neutralizing monoclonal antibodies induced by a synthetic peptide

PJ DURDA, LEE BACHELER, P CLAPHAM… - AIDS research and …, 1990 - liebertpub.com
We have developed a series of murine monoclonal antibodies to a region of the 120 kD
envelope glycoprotein (gp120) of human immunodeficiency virus type 1 (HIV-1). This region …

Characterization and epitope mapping of a human monoclonal antibody reactive with the envelope glycoprotein of human immunodeficiency virus.

B Banapour, K Rosenthal, L Rabin… - … (Baltimore, Md.: 1950 …, 1987 - journals.aai.org
A human monoclonal antibody (IgG2, lambda), 1B8. env, was produced, reactive with the
envelope glycoprotein of human immunodeficiency virus (HIV). The antibody specifically …

A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope.

TJ Palker, TJ Matthews, ME Clark… - Proceedings of the …, 1987 - National Acad Sciences
A highly immunogenic epitope from a conserved COOH-terminal region of the human
immunodeficiency virus (HIV) gp120 envelope protein has been identified with antisera from …

Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins.

PA Broliden, A von Gegerfelt… - Proceedings of the …, 1992 - National Acad Sciences
Four major neutralizing regions of the human immunodeficiency virus type 1 (HIV-1)
envelope glycoprotein were identified and characterized with a panel of 80 HIV-1 antibody …

Characteristics of a neutralizing monoclonal antibody to the HIV envelope glycoprotein

MA Skinner, R TING, AJ LANGLOIS… - AIDS research and …, 1988 - liebertpub.com
We have studied the biologic and physical properties of a monoclonal antibody that binds to
gp120, the exterior envelope glycoprotein of the human immunodeficiency virus (HIV) strain …

Another discontinuous epitope on glycoprotein gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibody.

DD Ho, MS Fung, YZ Cao, XL Li… - Proceedings of the …, 1991 - National Acad Sciences
To define the domains in the envelope glycoprotein important for antibody neutralization of
the human immunodeficiency virus type 1 (HIV-1), monoclonal antibodies (mAbs) were …

A broadly neutralizing monoclonal antibody that recognizes the V3 region of human immunodeficiency virus type 1 glycoprotein gp120.

T Ohno, M Terada, Y Yoneda… - Proceedings of the …, 1991 - National Acad Sciences
Previous studies have demonstrated that the principal neutralizing determinant of human
immunodeficiency virus type 1 (HIV-1) is located in the V3 loop of glycoprotein gp120 …

Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody.

WA Marasco, WA Haseltine… - Proceedings of the …, 1993 - National Acad Sciences
A single-chain antibody, derived from a human monoclonal antibody that recognizes the
CD4 binding region of the human immunodeficiency virus type 1 (HIV-1) envelope protein …