Large injuries to bones are still one of the most challenging musculoskeletal problems.
Tissue engineering can combine stem cells, scaffold biomaterials, and biofactors to aid in …

Bone tissue engineering has been continuously developing since the concept of “tissue
engineering” has been proposed. Biomaterials that are used as the basic material for the …

Bone disorders are of significant concern due to increase in the median age of our
population. Traditionally, bone grafts have been used to restore damaged bone. Synthetic …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Bone tissue has the capability to regenerate itself; however, defects of a critical size prevent
the bone from regenerating and require additional support. To aid regeneration, bone …

The management of bone defects is complicated by the presence of clinical conditions, such
as critical-sized defects created by high-energy trauma, tumour resection, infection, and …

The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

Bone tissue engineering uses the principles and methods of engineering and life sciences
to study bone structure, function and growth mechanism for the purposes of repairing …

Despite its intrinsic ability to regenerate form and function after injury, bone tissue can be
challenged by a multitude of pathological conditions. While innovative approaches have …

Millions of patients suffer yearly from bone fractures and disorders such as osteoporosis or
cancer, which constitute the most common causes of severe long-term pain and physical …