[HTML][HTML] Necroptosis molecular mechanisms: Recent findings regarding novel necroptosis regulators
Necroptosis is a form of programmed necrosis that is mediated by various cytokines and
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …
[HTML][HTML] Current translational potential and underlying molecular mechanisms of necroptosis
Cell death has a fundamental impact on the evolution of degenerative disorders,
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …
[HTML][HTML] Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression
Necroptosis, a form of regulated necrotic cell death, is mediated by receptor interacting
protein 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like protein (MLKL). However …
protein 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like protein (MLKL). However …
[HTML][HTML] Molecular insights into the mechanism of necroptosis: the necrosome as a potential therapeutic target
J Chen, R Kos, J Garssen, F Redegeld - Cells, 2019 - mdpi.com
Necroptosis, or regulated necrosis, is an important type of programmed cell death in addition
to apoptosis. Necroptosis induction leads to cell membrane disruption, inflammation and …
to apoptosis. Necroptosis induction leads to cell membrane disruption, inflammation and …
[HTML][HTML] Initiation and execution mechanisms of necroptosis: an overview
S Grootjans, T Vanden Berghe… - Cell Death & …, 2017 - nature.com
Necroptosis is a form of regulated cell death, which is induced by ligand binding to TNF
family death domain receptors, pattern recognizing receptors and virus sensors. The …
family death domain receptors, pattern recognizing receptors and virus sensors. The …
[HTML][HTML] Necroptosis: a regulated inflammatory mode of cell death
YK Dhuriya, D Sharma - Journal of neuroinflammation, 2018 - Springer
Programmed cell death has a vital role in embryonic development and tissue homeostasis.
Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis …
Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis …
[HTML][HTML] Necroptosis: a crucial pathogenic mediator of human disease
ME Choi, DR Price, SW Ryter, AMK Choi - JCI insight, 2019 - ncbi.nlm.nih.gov
Necroptosis is a genetically regulated form of necrotic cell death that has emerged as an
important pathway in human disease. The necroptosis pathway is induced by a variety of …
important pathway in human disease. The necroptosis pathway is induced by a variety of …
Complex roles of necroptosis in cancer
F Zhu, W Zhang, T Yang, S He - Journal of Zhejiang University-Science B, 2019 - Springer
Necroptosis is a tightly regulated form of necrosis that requires the activation of receptor-
interacting protein (RIP) kinases RIPK1 and RIPK3, as well as the RIPK3 substrate mixed …
interacting protein (RIP) kinases RIPK1 and RIPK3, as well as the RIPK3 substrate mixed …
[HTML][HTML] Necroptosis: a pathogenic negotiator in human diseases
Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …
scientific community because they are involved in diverse human diseases. Initially …
Necroptosis: mechanisms and relevance to disease
Necroptosis is a form of regulated cell death that critically depends on receptor-interacting
serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and …
serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and …