Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III

JS Allan, JE Coligan, F Barin, MF McLane, JG Sodroski… - Science, 1985 - science.org
Antibodies from the serum of patients with the acquired immune deficiency syndrome (AIDS)
or with the AIDS-related complex and from the serum of seropositive healthy homosexuals …

Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients

F Barin, MF McLane, JS Allan, TH Lee, JE Groopman… - Science, 1985 - science.org
In this study, two glycoproteins (gp160 and gp120) that are encoded by human T-cell
lymphoma virus type III (HTLV-III) were the antigens most consistently recognized by …

Antiserum to a synthetic peptide recognizes the HTLV-III envelope glycoprotein

RC Kennedy, RD Henkel, D Pauletti, JS Allan, TH Lee… - Science, 1986 - science.org
In a study performed to determine which regions of the human T-cell lymphotrophic virus
type III (HTLV-III) may represent vaccine candidates to prevent the acquired immune …

Antigens on HTLV-infected cells recognized by leukemia and AIDS sera are related to HTLV viral glycoprotein

J Schüpbach, MG Sarngadharan, RC Gallo - Science, 1984 - science.org
Cross-reactive antigens of molecular size of 61,000 to 68,000 daltons are found on the
surface of human cells infected by human T-cell leukemia-lymphoma virus (HTLV). They are …

Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients

WG Robey, B Safai, S Oroszlan, LO Arthur, MA Gonda… - Science, 1985 - science.org
The envelope (env) and structural (gag) gene products of human T-cell leukemia
(lymphotropic) virus type III were identified by immunoaffinity chromatography …

Binding of HTLV-III/LAV to T4+ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

JS McDougal, MS Kennedy, JM Sligh, SP Cort… - Science, 1986 - science.org
Human T-lymphotropic virus type III (HTLV-III) or lymphadenopathy-associated virus (LAV) is
tropic for human T cells with the helper-inducer phenotype, as defined by reactivity with …

Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS

MG Sarngadharan, M Popovic, L Bruch, J Schüpbach… - Science, 1984 - science.org
In cats, infection with T-lymphotropic retroviruses can cause T-cell proliferation and leukemia
or T-cell depletion and immunosuppression. In humans, some highly T4 tropic retroviruses …

A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients

JS Allan, JE Coligan, TH Lee, MF McLane, PJ Kanki… - Science, 1985 - science.org
A newly identified protein from HTLV-III/LAV, the virus implicated as the etiologic agent of the
acquired immune deficiency syndrome, was studied. This protein, which has a molecular …

HTLV-III in saliva of people with AIDS-related complex and healthy homosexual men at risk for AIDS

JE Groopman, SZ Salahuddin, MG Sarngadharan… - Science, 1984 - science.org
Peripheral blood leukocytes and saliva from 20 individuals, including four with the acquired
immune deficiency syndrome (AIDS), ten with AIDS-related complex (ARC), and six healthy …

Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene

FDM Veronese, AL DeVico, TD Copeland, S Oroszlan… - Science, 1985 - science.org
Radiolabeled amino acid sequencing was used to characterize gp41, an antigen of HTLV-
III/LAV, the virus believed to be the etiological agent of the acquired immune deficiency …