Objective: Cyclooxygenase-2 (COX-2) has been claimed to play role in carcinogenesis and
be related to a bad prognosis in tumours. The aim of this study was to investigate the …

Background: The aim of this study was to evaluate cyclooxygenase-2 (COX-2)
immunoreactivity in colorectal adenocarcinomas and to find correlations with different …

The aim of this study was to evaluate expression of COX-1 in renal cell carcinoma (RCC)
and its prognosticvalue. mRNA of COX-1 was detected in 42 paired RCC and adjacent …

Background: Colorectal carcinoma (CRC) is the most common neoplasm of the
gastrointestinal tract. COX-2 plays an important role in CRC development and is a key target …

Objective Breast carcinoma is the most common malignant tumor and the leading cause of
carcinoma deaths in women. Its etiology is multifactorial, implicating reproductive factors …

Background: Transitional cell carcinoma (TCC) is the most predominant type of urinary
bladder tumor. As cyclooxygenase (COX)-2 is recently introduced as an attractive target …

Background: COX-2 has been shown to play an important role in the development of breast
cancer and increased expression has been mooted as a poor prognostic factor. The …

Background: Cyclooxygenase 2 (COX-2) is important as an enzyme in the pathway leading
to the production of prostaglandin E2 (PGE2) and arachidonic acid. This pathway is known …

Two isoforms of cyclooxygenase, COX-1 and COX-2, have been identified and shown to be
involved in ‍tumorigenesis. Although, overexpression of COX-2 in human cancers has been …

Association of COX-2 8473T>C gene polymorphism with lung cancer risk. - Abstract - Europe
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