Tea catechins induce the conversion of preformed lysozyme amyloid fibrils to amorphous aggregates
J He, YF Xing, BO Huang, YZ Zhang… - Journal of agricultural …, 2009 - ACS Publications
Natural polyphenols are major constituents of plant foods and herbs. Numerous studies
have demonstrated that natural polyphenols inhibited amyloid formation and destabilized …
have demonstrated that natural polyphenols inhibited amyloid formation and destabilized …
Inhibition of amyloid fibrillation and cytotoxicity of lysozyme fibrillation products by polyphenols
S Shariatizi, AA Meratan, A Ghasemi… - International journal of …, 2015 - Elsevier
An increasing number of studies conducted under in vitro and in vivo conditions, have
concluded that polyphenols, compounds frequently occurring in many herbs with antioxidant …
concluded that polyphenols, compounds frequently occurring in many herbs with antioxidant …
(−)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme
Green tea polyphenols (GTPs) are found to be potent inhibitors of amyloid fibril formation.
We report the effective inhibitory property of (−)-epicatechin gallate (ECG) during the alkali …
We report the effective inhibitory property of (−)-epicatechin gallate (ECG) during the alkali …
Gallic acid induced dose dependent inhibition of lysozyme fibrillation
Amyloidosis is primarily characterized by the deposition of misfolded protein aggregates.
Although the natural polyphenols have long been known as effective amyloid inhibitors, the …
Although the natural polyphenols have long been known as effective amyloid inhibitors, the …
[HTML][HTML] Effect of fibrillation conditions on the anti-amyloidogenic properties of polyphenols and their involved mechanisms
In the present study, we have investigated the effects of protein concentration and stirring on
the in vitro assembly of Hen Egg White Lysozyme (HEWL), particularly with regard to the …
the in vitro assembly of Hen Egg White Lysozyme (HEWL), particularly with regard to the …
Inhibition of islet amyloid polypeptide fibrillation by structurally diverse phenolic compounds and fibril disaggregation potential of rutin and quercetin
The influence of 12 food-derived phenolic compounds on islet amyloid polypeptide (IAPP)
fibrillation was investigated. Results from thioflavin T assay demonstrated that gallic acid …
fibrillation was investigated. Results from thioflavin T assay demonstrated that gallic acid …
[HTML][HTML] Oxidized epigallocatechin gallate inhibited lysozyme fibrillation more strongly than the native form
TT An, S Feng, CM Zeng - Redox Biology, 2017 - Elsevier
Epigallocatechin gallate (EGCG), the most abundant flavanoid in green tea, is currently
being evaluated in the clinic due to its benefits in the treatment of amyloid disorders. Its anti …
being evaluated in the clinic due to its benefits in the treatment of amyloid disorders. Its anti …
Effect of curcumin on the amyloid fibrillogenesis of hen egg-white lysozyme
SSS Wang, KN Liu, WH Lee - Biophysical chemistry, 2009 - Elsevier
At least twenty human proteins can fold abnormally to form pathological deposits that are
associated with several degenerative diseases. Despite extensive investigation on amyloid …
associated with several degenerative diseases. Despite extensive investigation on amyloid …
[HTML][HTML] Green tea leaf constituents inhibit the formation of lysozyme amyloid aggregates: An effect of mutual interactions
Amyloidoses represent a group of pathological conditions characterized by amyloid fibrils
accumulating in the form of deposits in intra-or extracellular space, leading to tissue …
accumulating in the form of deposits in intra-or extracellular space, leading to tissue …
Myricetin prevents fibrillogenesis of hen egg white lysozyme
J He, Y Wang, AK Chang, L Xu, N Wang… - Journal of agricultural …, 2014 - ACS Publications
Myricetin is a natural flavonol found in many grapes, berries, fruits, vegetables, and herbs as
well as other plants. Recent studies have identified potential antiamyloidogenic activity for …
well as other plants. Recent studies have identified potential antiamyloidogenic activity for …