Mitochondria are crucial sites for biological oxidation and substance metabolism and plays a
vital role in maintaining intracellular homeostasis. When mitochondria undergo oxidative …

The development of enzyme mimetics that clear excess mitochondrial reactive oxidative
stress (ROS) could provide effective treatment for a wide variety of diseases. Herein …

Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

Mitochondrial research has made an enormous leap since mitochondrial DNA mutations
were identified as a primary cause for human diseases in 1988 and the organelle's crucial …

Due to the pivotal role of mitochondria in the generation of adenosine triphosphate (ATP)
and the regulation of cellular homeostasis, mitochondrial dysfunction may exert a profound …

Cancer remains one of the leading causes of death worldwide, both in developed and in
developing nations. It may affect people of all ages, even fetuses, but the risk for most cancer …

Nanozyme is a type of nanostructured material with intrinsic enzyme mimicking activity,
which has been increasingly studied in the biological field. Compared with natural enzymes …

Abstract Development of enzyme mimics for the scavenging of excessive mitochondrial
superoxide (O2•−) can serve as an effective strategy in the treatment of many diseases …

Mitochondrial dysfunction including oxidative stress and DNA mutations underlies the
pathology of various diseases including Alzheimer's disease and diabetes, necessitating the …

A variety of diseases including neurodegenerative, neuromuscular diseases, diabetes,
obesity and cancer are considered to be caused by mitochondrial dysfunction. Efficient …