Database mining and animal experiment-based validation of the efficacy and mechanism of Radix Astragali (Huangqi) and Rhizoma Atractylodis Macrocephalae …

C Zhang, W Guo, X Yao, J Xia, Z Zhang, J Li… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance In China, Traditional Chinese medicine (TCM) is
often used as the main therapy for cancer-related fatigue (CRF). However, there is limited …

Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression

J He, D Han, C Jia, J Xie, F Zhu, J Wei, D Li… - Drug Design …, 2023 - Taylor & Francis
Purpose To investigate the mechanisms of antidepressant action of active fraction of
Polyrhachis vicina Rogers (AFPR) through network pharmacology, molecular docking and …

[HTML][HTML] Natural formulas and the nature of formulas: exploring potential therapeutic targets based on traditional Chinese herbal formulas

Q Zhang, H Yu, J Qi, D Tang, X Chen, J Wan, P Li… - PLoS …, 2017 - journals.plos.org
By comparing the target proteins (TPs) of classic traditional Chinese medicine (TCM) herbal
formulas and modern drugs used for treating coronary artery disease (CAD), this study …

[HTML][HTML] A bioinformatics investigation into the pharmacological mechanisms of the effect of Fufang Danshen on pain based on methodologies of network …

Y Sun, J Yang - Scientific Reports, 2019 - nature.com
Abstract Fufang Danshen (FFDS), a Chinese medicine formula widely used in the clinic, has
proven therapeutic effects on pain relief. However, the mechanisms of these effects have not …

Systematic elucidation of the bioactive alkaloids and potential mechanism from Sophora flavescens for the treatment of eczema via network pharmacology

Y Lin, XJ Chen, L He, XL Yan, QR Li, X Zhang… - Journal of …, 2023 - Elsevier
Ethnopharmacology relevance Sophora flavescens is a frequently used traditional Chinese
medicine (TCM) for the treatment of skin disorders, diarrhea, vaginal itching and …

Investigation of the Potential Mechanism of Alpinia officinarum Hance in Improving Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking

X Zhang, X Li, H Li, M Zhou, Y Zhang… - Evidence‐Based …, 2023 - Wiley Online Library
Objective. We used network pharmacology, molecular docking, and cellular analysis to
explore the pharmacodynamic components and action mechanism of Alpinia officinarum …

[HTML][HTML] East Asian herbal medicine to reduce primary pain and adverse events in Cancer Patients: A systematic review and meta-analysis with association rule …

HG Jo, J Seo, S Choi, D Lee - Frontiers in Pharmacology, 2022 - frontiersin.org
Objective: Cancer pain is an important factor in cancer management that affects a patient's
quality of life and survival-related outcomes. The aim of this review was to systematically …

An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin

B Zhang, X Wang, S Li - Evidence‐based Complementary and …, 2013 - Wiley Online Library
The scientific understanding of traditional Chinese medicine (TCM) has been hindered by
the lack of methods that can explore the complex nature and combinatorial rules of herbal …

A network pharmacology study with molecular docking to investigate the possibility of licorice against posttraumatic stress disorder

ZK Qiu, ZT Liu, JL Pang, HB Wu, X Liu, ZM Yang… - Metabolic Brain …, 2021 - Springer
Post traumatic stress disorder (PTSD) is a mental health condition that has a debilitating
effect on a person's quality of life and leads to a high socioeconomic burden. Licorice has …

[Retracted] Network Pharmacology Analysis on the Mechanism of Huangqi Sijunzi Decoction in Treating Cancer‐Related Fatigue

Y Cui, H Wang, D Wang, J Mi, G Chen… - Journal of healthcare …, 2021 - Wiley Online Library
Objective. This study aimed to determine the active ingredients of Huangqi Sijunzi Decoction
(HQSJZD) and the targets in treating cancer‐related fatigue (CRF) so as to investigate the …