Identification of a neutralization epitope on the envelope gp46 antigen of human T cell leukemia virus type I and induction of neutralizing antibody by peptide …

Y Tanaka, L Zeng, H Shiraki, H Shida… - Journal of immunology …, 1991 - journals.aai.org
We have generated a number of mAb against various epitopes on the external envelope
glycoprotein, gp46, of human T cell leukemia virus type I (HTLV-I) from a WKA rat immunized …

Induction of antibody responses that neutralize human T-cell leukemia virus type I infection in vitro and in vivo by peptide immunization

Y Tanaka, R Tanaka, E Terada, Y Koyanagi… - Journal of …, 1994 - Am Soc Microbiol
In order to define neutralization regions on the envelope antigen of human T-cell leukemia
virus type I (HTLV-I), we have generated a number of new anti-envelope gp46 monoclonal …

Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a …

TJ Palker, ME Tanner, RM Scearce… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
Antigenic sites on human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope
glycoproteins that are immunogenic in man were studied with envelope gene (env)-encoded …

Identification of new epitopes recognized by human monoclonal antibodies with neutralizing and antibody-dependent cellular cytotoxicity activities specific for human …

M Kuroki, M Nakamura, Y Itoyama… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
We have generated a number of EBV-transformed B cell lines producing human mAb
against human T cell leukemia virus type 1 (HTLV-1) from the peripheral blood B …

Identification and synthesis of the epitope for a human monoclonal antibody which can neutralize human T-cell leukemia/lymphotropic virus type I

S Ralston, P Hoeprich, R Akita - Journal of Biological Chemistry, 1989 - Elsevier
A monoclonal antibody (mAb), designated 0.5 α, derived from a patient with adult T-cell
leukemia was found previously to neutralize the human T-cell leukemia/lymphotropic type I …

Identification of type-specific linear epitopes in the glycoproteins gp46 and gp21 of human T-cell leukemia viruses type I and type II using synthetic peptides.

P Horal, WW Hall, BO Svennerholm… - Proceedings of the …, 1991 - National Acad Sciences
Synthetic peptides of 20-25 amino acids were employed in enzyme-linked immunosorbent
assays to identify linear epitopes in the external glycoprotein gp46 and the transmembrane …

Multiple neutralizing B-cell epitopes of human T-cell leukemia virus type 1 (HTLV-1) identified by human monoclonal antibodies. A basis for the design of an HTLV-1 …

E Baba, M Nakamura, Y Tanaka, M Kuroki… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
We have generated 153 human mAb reacting with natural envelope glycoprotein-gp46 of
human T-cell leukemia virus type-1 (HTLV-1) by the EBV-transformation of B lymphocytes …

A peptide-based human T cell leukemia virus type I vaccine containing T and B cell epitopes that induces high titers of neutralizing antibodies.

E Baba, M Nakamura, K Ohkuma, J Kira… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
We have recently identified the principal linear neutralizing B cell epitopes of human T cell
leukemia virus type I (HTLV-I) on the envelope protein gp46, amino acids (aa) 187-199, by …

Detection of antibodies to human T-lymphotropic virus type III by using a synthetic peptide of 21 amino acid residues corresponding to a highly antigenic segment of …

JJ Wang, S Steel, R Wisniewolski… - Proceedings of the …, 1986 - National Acad Sciences
A peptide of 21 amino acids with the sequence Arg-Ile-Leu-Ala-Val-Glu-Arg-Tyr-Leu-Lys-
Asp-Gln-Gln-Leu-Leu-Gly-Ile-Trp-Gly-Cys-Ser encoded by a segment in the env gene of …

Generation and characterization of monoclonal antibodies against multiple epitopes on the C‐terminal half of envelope gp46 of human T‐cell leukemia virus type‐I …

Y Tanaka, M Yasumoto, H Nyunoya… - … journal of cancer, 1990 - Wiley Online Library
In order to study the antigenicity of envelope 46 kDa glycoprotein (gp46) of human T‐cell
leukemia virus type‐l (HTLV‐I), we have generated monoclonal anti‐gp46 antibodies …