Multiple acyl-coenzyme A dehydrogenase deficiency (MADD), or glutaric aciduria type II
(GAII), is a group of clinically heterogeneous disorders caused by mutations in electron …

FAD synthetase (FADS)(EC 2.7. 7.2) is a key enzyme in the metabolic pathway that converts
riboflavin into the redox cofactor FAD. Two hypothetical human FADSs, which are the …

Absorption of riboflavin is mediated by transporter (s). However, a mammalian riboflavin
transporter has yet to be identified. In the present study, the novel human and rat riboflavin …

As an essential vitamin, the role of riboflavin in human diet and health is increasingly being
highlighted. Insufficient dietary intake of riboflavin is often reported in nutritional surveys and …

Riboflavin, or vitamin B2, is a precursor to flavin adenine dinucleotide (FAD) and flavin
mononucleotide (FMN) molecules, required in biological oxidation‐reduction reactions. We …

Mitochondria are the repository for various metabolites involved in diverse energy-
generating processes, like the TCA cycle, oxidative phosphorylation, and metabolism of …

Riboflavin, commonly known as vitamin B2, is the precursor of flavin cofactors. It is present in
our typical diet, and inside the cells it is metabolized to FMN and FAD. As a result of their …

Vitamin B2, riboflavin is essential for cellular function, as it participates in a diversity of redox
reactions central to human metabolism, through its role as precursor for the cofactors flavin …

We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

Riboflavin (vitamin B-2) was first isolated from milk whey in the late 1870s as the water-
soluble, yellowish pigment called lactochrome. By the 1930s, lactochrome was structurally …