We have newly identified rat riboflavin transporter 2 (rRFT2) and its human orthologue
(hRFT2), and carried out detailed functional characterization of rRFT2. The mRNA of rRFT2 …

Riboflavin (vitamin B2) serves as the precursor for FMN and FAD in almost all organisms
that utilize the redox‐active isoalloxazine ring system as a coenzyme in enzymatic reactions …

Flavin-dependent monooxygenases and oxidoreductases are located at critical branch
points in the biosynthesis and metabolism of cholesterol and vitamin D. These flavoproteins …

Background: FAD synthase is known to catalyze the biosynthesis of FAD in cytosol and
mitochondria. Results: The existence of a nuclear FAD synthase and a FAD-hydrolyzing …

Multiple acyl-CoA dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII) is
most often caused by mutations in the genes encoding the α-or β-subunit of electron transfer …

Abstract Brown-Vialetto-Van Laere syndrome (BVVLS [MIM 211530]) is a rare neurological
disorder characterized by infancy onset sensorineural deafness and ponto-bulbar palsy …

Introduction Riboflavin (vitamin B2) is absorbed in the small intestine by the human
riboflavin transporters RFVT1 and RFVT3. A third riboflavin transporter (RFVT2) is …

We have studied the functional steps by which Saccharomyces cerevisiae mitochondria can
synthesize FAD from cytosolic riboflavin (Rf). Riboflavin uptake into mitochondria took place …

Riboflavin is a water-soluble vitamin (vitamin B 2) required for the production of the flavin
cofactors FMN and FAD. Mammals are unable to synthesize riboflavin and need a dietary …

Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are essential
coenzymes in redox reactions. For example, FAD is a coenzyme for both glutathione …