Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …

Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …

Pyrazolines remain privileged heterocycles in drug discovery. 2-Pyrazoline scaffold has
been proven as a ubiquitous motif which is present in a number of pharmacologically …

Heterocycles are common in the structure of drugs used clinically to deal with diseases.
Such drugs usually contain nitrogen, oxygen and sulfur, which possess electron-accepting …

Introduction: Pyrazolines are well-known and important nitrogen-containing five-membered
ring heterocyclic compounds. Various methods have been worked out for their synthesis …

The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …

Identification of potent anticancer agents with high selectivity and low toxicity remains on the
way to human health. Pyridazine featuring advantageous physicochemical properties and …

Pyrazoline is an important five membered nitrogen heterocycle, which has been extensively
researched upon. The ring is quite stable and has inspired chemists to carry out various …

Pyran is an oxygen-containing heterocyclic moiety, which exhibits an array of
pharmacological properties. Pyran is also one of the important structural subunits found …

Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …