Antiserum to a synthetic peptide recognizes the HTLV-III envelope glycoprotein

RC Kennedy, RD Henkel, D Pauletti, JS Allan, TH Lee… - Science, 1986 - science.org
In a study performed to determine which regions of the human T-cell lymphotrophic virus
type III (HTLV-III) may represent vaccine candidates to prevent the acquired immune …

Induction of anti‐HIV neutralizing antibodies by synthetic peptides.

TC Chanh, GR Dreesman, P Kanda, GP Linette… - The EMBO …, 1986 - embopress.org
Two synthetic peptides containing amino acid sequences analogous to the envelope
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …

Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III

JS Allan, JE Coligan, F Barin, MF McLane, JG Sodroski… - Science, 1985 - science.org
Antibodies from the serum of patients with the acquired immune deficiency syndrome (AIDS)
or with the AIDS-related complex and from the serum of seropositive healthy homosexuals …

HTLV-III/LAV-Neutralizing Antibodies to an E. coli-Produced Fragment of the Virus Envelope

SD Putney, TJ Matthews, WG Robey, DL Lynn… - Science, 1986 - science.org
Immunization with either an Escherichia coli recombinant segment of the human T-cell
lymphotropic virus (HTLV-III/LAV) envelope protein (gp120) or with deglycosylated gp120 …

Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients

F Barin, MF McLane, JS Allan, TH Lee, JE Groopman… - Science, 1985 - science.org
In this study, two glycoproteins (gp160 and gp120) that are encoded by human T-cell
lymphoma virus type III (HTLV-III) were the antigens most consistently recognized by …

Binding of HTLV-III/LAV to T4+ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

JS McDougal, MS Kennedy, JM Sligh, SP Cort… - Science, 1986 - science.org
Human T-lymphotropic virus type III (HTLV-III) or lymphadenopathy-associated virus (LAV) is
tropic for human T cells with the helper-inducer phenotype, as defined by reactivity with …

Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients

WG Robey, B Safai, S Oroszlan, LO Arthur, MA Gonda… - Science, 1985 - science.org
The envelope (env) and structural (gag) gene products of human T-cell leukemia
(lymphotropic) virus type III were identified by immunoaffinity chromatography …

Sequence of the envelope glycoprotein gene of type II human T lymphotropic virus

J Sodroski, R Patarca, D Perkins, D Briggs, TH Lee… - Science, 1984 - science.org
The sequence of the envelope glycoprotein gene of type II human T lymphotropic virus
(HTLV) is presented. The predicted amino acid sequence is similar to that of the …

A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients

JS Allan, JE Coligan, TH Lee, MF McLane, PJ Kanki… - Science, 1985 - science.org
A newly identified protein from HTLV-III/LAV, the virus implicated as the etiologic agent of the
acquired immune deficiency syndrome, was studied. This protein, which has a molecular …

Expression in Escherichia coli of Open Reading Frame Gene Segments of HTLV-III

NT Chang, PK Chanda, AD Barone, S McKinney… - Science, 1985 - science.org
Human T-cell lymphotropic virus type III (HTLV-III), the causative agent of the acquired
immune deficiency syndrome (AIDS), was recently isolated and its genomic structure …