The monoclonal antibody that recognizes an epitope in the C-terminal region of the fibrinogen α-chain reacts with soluble fibrin and fibrin monomer generated by …
A Suzuki, H Ebinuma, M Matsuo, O Miyazaki… - Thrombosis research, 2007 - Elsevier
INTRODUCTION: The presence of soluble fibrin (SF) provides evidence of thrombin
activation in the blood; therefore, SF is a useful marker for diagnosing blood coagulation …
activation in the blood; therefore, SF is a useful marker for diagnosing blood coagulation …
A novel monoclonal antibody to fibrin monomer and soluble fibrin for the detection of soluble fibrin in plasma
A Hamano, S Tanaka, Y Takeda, M Umeda, Y Sakata - Clinica chimica acta, 2002 - Elsevier
Background: Soluble fibrin (SF), composed of fibrin monomer (FM) and fibrinogen, is well
known to exist in the circulating blood derived from patients with thrombotic diseases, and its …
known to exist in the circulating blood derived from patients with thrombotic diseases, and its …
Characterization of a monoclonal antibody specific to the amino terminus of the α-chain of human fibrin
SJT Mao, AE Rechtin, JL Krstenansky… - Thrombosis and …, 1990 - thieme-connect.com
A peptide, Gly-Pro-Arg-Val-Val-Glu, corresponding to the first six residues of the amino
terminus of the a-chain of human fibrin (desAA-fihrin) was prepared by solid-phase peptide …
terminus of the a-chain of human fibrin (desAA-fihrin) was prepared by solid-phase peptide …
Measurement of soluble fibrin monomer-fibrinogen complex in plasmas derived from patients with various underlying clinical situations
K Nakahara, Y Kazahaya, Y Shintani… - Thrombosis and …, 2003 - thieme-connect.com
We previously reported a monoclonal antibody named IF-43 that specifically recognizes
thrombin-modified fibrinogen (desAA-and desAABB-fibrin monomer) bound with fibrinogen …
thrombin-modified fibrinogen (desAA-and desAABB-fibrin monomer) bound with fibrinogen …
Characterisation of the chains of human fibrinogen isolated by perfusion chromatography using fibrin specific monoclonal antibodies
S Raut, PH Corran, PJ Gaffney - Thrombosis research, 1995 - Elsevier
In order to study the epitopes on fibrin to which monoclonal antibodies are directed, we
required pure individual polypeptide chains of human fibrinogen in milligram quantities …
required pure individual polypeptide chains of human fibrinogen in milligram quantities …
Soluble fibrin monomer degradation products as a potentially useful marker for hypercoagulable states with accelerated fibrinolysis
M Ieko, T Nakabayashi, T Tarumi, S Naito, M Yoshida… - Clinica Chimica …, 2007 - Elsevier
BACKGROUND: Fibrin monomer (FM) and its complex (sFC) exist at high concentrations in
hypercoagulable state blood. Two novel immunoassays for sFC (SF and FMC) using specific …
hypercoagulable state blood. Two novel immunoassays for sFC (SF and FMC) using specific …
Fibrin Detected in Plasma of Patients with Disseminated intravascuiar Coagulation by Fibrin-specific Antibodies Consists Primarily of High Molecular Weight Factor …
SA Pfitzner, CE Dempfle, M Matsuda… - Thrombosis and …, 1997 - thieme-connect.com
Pooled plasma from 40 patients with severe disseminated intravascuiar coagulation (DIC)
secondary to septic conditions was subjected to gel permeation chromatography on …
secondary to septic conditions was subjected to gel permeation chromatography on …
A monoclonal antibody that recognizes a neo-antigen exposed in the E domain of fibrin monomer complexed with fibrinogen or its derivatives: its application to the …
G Soe, I Kohno, K Inuzuka, Y Itoh, M Matsuda - 1996 - ashpublications.org
Using urea-solubilized human fibrin monomer as an immunogen, we raised in mice a
battery of monoclonal antibodies that reacted with the immunogen but not with urea-treated …
battery of monoclonal antibodies that reacted with the immunogen but not with urea-treated …
A monoclonal antibody, specific for human fibrinogen, fibrinopeptide A-containing fragments and not reacting with free fibrinopeptide A
PW Koppert, CM Huijsmans, W Nieuwenhuizen - 1985 - ashpublications.org
Spleen cells of BALB/c mice, immunized with fragments Y of normal human fibrinogen, were
fused with P3 X 63 Ag 8653 myeloma cells. A clone was found which produces monoclonal …
fused with P3 X 63 Ag 8653 myeloma cells. A clone was found which produces monoclonal …
Effects of an antifibrin monoclonal antibody and fragments thereof on some properties of fibrin
M Wasser, M Welling, G Lamers… - Thrombosis and …, 1990 - thieme-connect.com
Antifibrin monoclonal antibody Y22, of IgG 1-subclass, has its epitope in the D-domain of
fibrin. In a thrombin time assay, Y22 and its F (ab) 2 fragments interfere with clotting of …
fibrin. In a thrombin time assay, Y22 and its F (ab) 2 fragments interfere with clotting of …