[HTML][HTML] Attenuation of inflammatory bowel disease by oral administration of mucoadhesive polydopamine-coated yeast β-glucan via ROS scavenging and gut …

F Yang, Y Su, C Yan, T Chen, PCK Cheung - Journal of …, 2024 - Springer
Abstract Treatment for inflammatory bowel disease (IBD) is challenging since current anti-
inflammatory and immunosuppressive therapies do not address the underlying causes of …

Polyphenolic Nanoparticle-Modified Probiotics for Microenvironment Remodeling and Targeted Therapy of Inflammatory Bowel Disease

Q Hu, J Li, T Wang, X Xu, Y Duan, Y Jin - ACS nano, 2024 - ACS Publications
Inflammatory bowel diseases (IBDs) refer to multifaceted disorders in the intestinal
microenvironment and microbiota homeostasis. In view of the broad bioactivity and high …

[HTML][HTML] Rhubarb polysaccharide and berberine co-assembled nanoparticles ameliorate ulcerative colitis by regulating the intestinal flora

Y Feng, C Wu, H Chen, T Zheng, H Ye… - Frontiers in …, 2023 - frontiersin.org
Introduction: Inflammatory bowel disease (IBD) affects about 7 million people globally, which
is a chronic inflammatory condition of the gastrointestinal tract caused by gut microbiota …

β-1, 3-d-glucan particles-based “nest” protected co-loaded Rhein and Emodin regulates microbiota and intestinal immunity for ulcerative colitis treatment

Y Wang, S Zhong, K Yang, R Luo, L Dai… - International Journal of …, 2024 - Elsevier
Abstract Herein, a β-1, 3-D-glucan based yeast cell wall loaded with co-loaded
nanoparticles of Rhein (RH) and Emodin (EMO), was developed for the combined treatment …

Colon-Targeting Angelica sinensis Polysaccharide Nanoparticles with Dual Responsiveness for Alleviation of Ulcerative Colitis

Y Xu, BW Zhu, R Sun, X Li, D Wu… - ACS Applied Materials & …, 2023 - ACS Publications
Intestinal immune dysfunction and gut microbiota dysbiosis are critically causative factors in
the pathogenesis of ulcerative colitis (UC); however, the current first-line drugs for UC …

[HTML][HTML] Berberine-loaded carboxylmethyl chitosan nanoparticles ameliorate DSS-induced colitis and remodel gut microbiota in mice

L Zhao, X Du, J Tian, X Kang, Y Li, W Dai… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a refractory disorder characterized by chronic and
recurrent inflammation. The progression and pathogenesis of IBD is closely related to …

ROS Scavenging and inflammation-directed polydopamine nanoparticles regulate gut immunity and flora therapy in inflammatory bowel disease

M Bao, K Wang, J Li, Y Li, H Zhu, M Lu, Y Zhang… - Acta Biomaterialia, 2023 - Elsevier
Dysfunction of the intestinal mucosal immune system and dysbiosis of the intestinal
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …

Gastrointestinal Microenvironment Responsive Nanoencapsulation of Probiotics and Drugs for Synergistic Therapy of Intestinal Diseases

P Peng, T Feng, X Yang, C Nie, L Yu, R Ding, Q Zhou… - ACS …, 2023 - ACS Publications
The gut microbiota are prominent in preserving intestinal environmental homeostasis and
managing human health, and their dysbiosis has been directly related to many kinds of …

Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease

P Peng, T Feng, X Yang, R Ding, J Wang… - Journal of Controlled …, 2024 - Elsevier
Inflammatory bowel disease (IBD) is closely associated with dysregulated immune
response, gut mucosal barrier, and microbiota. Conventional treatments suffer from inferior …

[HTML][HTML] Enzyme-like biomimetic oral-agent enabling modulating gut microbiota and restoring redox homeostasis to treat inflammatory bowel disease

Z Shi, X Li, J Chen, Z Dai, Y Zhu, T Wu, Q Liu, H Qin… - Bioactive Materials, 2024 - Elsevier
Reactive oxygen species (ROS), immune dysregulation-induced inflammatory outbreaks
and microbial imbalance play critical roles in the development of inflammatory bowel …