Modeling the pasture-associated severe equine asthma bronchoalveolar lavage fluid proteome identifies molecular events mediating neutrophilic airway inflammation
Background: Pasture-associated severe equine asthma is a warm season, environmentally-
induced respiratory disease characterized by reversible airway obstruction, persistent and …
induced respiratory disease characterized by reversible airway obstruction, persistent and …
Gene expression analysis to assess the relevance of rodent models to human lung injury
The relevance of animal models to human diseases is an area of intense scientific debate.
The degree to which mouse models of lung injury recapitulate human lung injury has never …
The degree to which mouse models of lung injury recapitulate human lung injury has never …
A semi-quantitative scoring system for green histopathological evaluation of large animal models of acute lung injury
Acute respiratory distress syndrome (ARDS) is a life-threatening, high mortality pulmonary
condition characterized by acute lung injury (ALI) resulting in diffuse alveolar damage …
condition characterized by acute lung injury (ALI) resulting in diffuse alveolar damage …
Conflict between direct experience and research-based evidence is a key challenge to evidence-based respiratory medicine on British racing yards
T Kinnison, JM Cardwell - Frontiers in veterinary science, 2020 - frontiersin.org
Inflammatory airway disease (IAD) is a commonly diagnosed but variably defined syndrome
of equine lower airway inflammation. The most recent American College of Veterinary …
of equine lower airway inflammation. The most recent American College of Veterinary …
Real time RT-PCR analysis of inflammatory mediator expression in recurrent airway obstruction-affected horses
E Padoan, S Ferraresso, S Pegolo… - Veterinary Immunology …, 2013 - Elsevier
The goal of the present study was to investigate mRNA expression levels of several
cytokines and inflammatory mediators in broncho-alveolar lavage (BAL) fluid and respiratory …
cytokines and inflammatory mediators in broncho-alveolar lavage (BAL) fluid and respiratory …
Evaluation of cytokine mRNA expression in bronchoalveolar lavage cells from horses with inflammatory airway disease
KJ Hughes, L Nicolson, N Da Costa, SH Franklin… - Veterinary Immunology …, 2011 - Elsevier
Inflammatory airway disease (IAD) is a common disorder of performance horses and is
associated with poor performance and accumulation of mucus and inflammatory cells in …
associated with poor performance and accumulation of mucus and inflammatory cells in …
[HTML][HTML] Assessing pulmonary pathology by detailed examination of respiratory function
LJ Vaickus, J Bouchard, J Kim, S Natarajan… - The American journal of …, 2010 - Elsevier
Pulmonary inflammation causes multiple alterations within the lung, including mucus
production, recruitment of inflammatory cells, and airway hyperreactivity (AHR) …
production, recruitment of inflammatory cells, and airway hyperreactivity (AHR) …
A comparison of pro-inflammatory cytokine mRNA expression in equine bronchoalveolar lavage (BAL) and peripheral blood
S Hansen, KE Baptiste, J Fjeldborg… - Veterinary immunology …, 2014 - Elsevier
An imbalance in various cytokine mRNA expression in bronchoalveolar lavage (BAL) and
peripheral blood mononuclear cells (PBMC) in horses suffering from recurrent airway …
peripheral blood mononuclear cells (PBMC) in horses suffering from recurrent airway …
Cytokine mRNA expression of pulmonary macrophages varies with challenge but not with disease state in horses with heaves or in controls
Heaves in horses is characterized by lower airway neutrophilic inflammation, and reversible
airflow obstruction. Pulmonary macrophages contribute to the inflammation observed in a …
airflow obstruction. Pulmonary macrophages contribute to the inflammation observed in a …