An official American thoracic society workshop report: comparative pathobiology of fibrosing lung disorders in humans and domestic animals

J Roman, KK Brown, A Olson, BM Corcoran… - Annals of the …, 2013 - atsjournals.org
Background: The clinical outcome of idiopathic pulmonary fibrosis (IPF) is poor, with a 50%
survival rate at 3 years. Furthermore, current treatments provide little amelioration of …

Early biomarkers of inflammation in dogs and cats: the acute phase proteins.

S Paltrinieri - Veterinary Research Communications, 2007 - search.ebscohost.com
Early Biomarkers of Inflammation in Dogs and Cats: The Acute Phase Proteins Page 1 Early
Biomarkers of Inflammation in Dogs and Cats: The Acute Phase Proteins S. Paltrinieri …

Variability of neutrophil and pulmonary alveolar macrophage function in swine

JM Du Manoir, BN Albright, G Stevenson… - Veterinary immunology …, 2002 - Elsevier
Neutrophils and alveolar macrophages are essential defence mechanisms against bacterial
infection of the lung. The purpose of this study was to evaluate the variability of a panel of …

Measuring lung function in murine models of pulmonary disease

PD Sly, DJ Turner, Z Hantos - Drug Discovery Today: Disease Models, 2004 - Elsevier
Mice are commonly used to model human lung diseases. However, their small size poses
substantial problems for accurately measuring lung function. Non-invasive techniques have …

Modeling inflammation in the zebrafish: how a fish can help us understand lung disease

SA Renshaw, CA Loynes, S Elworthy… - Experimental lung …, 2007 - Taylor & Francis
Neutrophilic inflammation is responsible for much of the tissue damage seen in many lung
diseases. For resolution of inflammation to occur, neutrophils must die by apoptosis …

[PDF][PDF] The ARRIVE guidelines-Examples Animal Research: Reporting In Vivo Experiments

C Kilkenny, WJ Browne, IC Cuthill, M Emerson… - National Centre for the …, 2010 - Citeseer
BACKGROUND AND PURPOSE: Asthma is an inflammatory disease that involves airway
hyperresponsiveness and remodelling. Flavonoids have been associated to anti …

The opportunities and challenges of developing imaging biomarkers to study lung function and disease

DP Schuster - American journal of respiratory and critical care …, 2007 - atsjournals.org
Recent advances in imaging offer exciting opportunities to develop and validate lung-
specific biomarkers as valuable adjuncts to diagnosis, tests of treatment efficacy, and/or …

Alternatives for Lung Research: Stuck between a Rat and a Hard Place: The Twelfth FRAME Annual Lecture (the Sixth Bill Annett Lecture) presented at the Kennel …

KA BéruBé - Alternatives to Laboratory Animals, 2011 - journals.sagepub.com
The respiratory system acts as a portal into the human body for airborne materials, which
may gain access via the administration of medicines or inadvertently during inhalation of …

Mechanistic understanding of lung inflammation: recent advances and emerging techniques

C Keskinidou, AG Vassiliou, I Dimopoulou… - Journal of …, 2022 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is a life-threatening lung injury characterized by
an acute inflammatory response in the lung parenchyma. Hence, it is considered as the most …

Stress alters the cellular and proteomic compartments of bovine bronchoalveolar lavage fluid

GB Mitchell, ME Clark, M Siwicky, JL Caswell - Veterinary immunology and …, 2008 - Elsevier
The stresses of transportation, weaning and commingling are associated with an increased
incidence of bacterial and viral pneumonia in cattle. Proteins expressed in the epithelial …