Background: Cancer is the second leading cause of death worldwide and each year tens of
millions of people are lost their lives due to different types of cancer. Despite all efforts in the …

Cancer is one of the leading causes of global mortality and morbidity. It is caused by
dysregulation of key cellular processes. Treatment of cancer focuses on re-regulation of …

Cancer is a prominent cause of death globally. Currently, many drugs that are in clinical
practice are having a high prevalence of side effect and multidrug resistance. Risk of tumors …

Cancer stands as a prominent global cause of death. One of the key reasons why clinical
tumor chemotherapy fails is multidrug resistance (MDR). In recent decades, accumulated …

Multidrug resistance (MDR) is a critical problem in cancer chemotherapy. Cancer cells can
develop resistance not only to a single cytotoxic drug, but also to entire classes of …

Multidrug resistance (MDR) in cancer cells can lead to chemotherapeutic failure. The lack of
effective therapies has created a growing need for developing new and effective …

One can recognize multidrug resistance (MDR) and residue as a biggest difficulty in cancer
specialist. Chemotherapy-resistant cancer may be successfully treated by combining MDR …

One of the greatest challenges in cancer treatment is the intrinsic development of multidrug
resistance (MDR). Several hypotheses with experimental evidence, such as altered drug …

Plant secondary metabolites (SMs) common natural occurrences and the significantly lower
toxicities of many SM have led to the approaching development and use of these …

Resistance to chemotherapeautic drugs is one of the main obstacles to effective cancer
treatment. Multidrug resistance (MDR) is defined as resistance to structurally and/or …